Suppr超能文献

耳穴疗法、一种草药复方(阿斯莱格胶囊)和二甲双胍对多囊卵巢综合征临床症状影响的比较:随机临床试验

Comparison of the Effect of Auriculotherapy, a Herbal Compound (Aslagh Capsule), and Metformin on the Clinical Symptoms of Polycystic Ovary Syndrome: Randomized Clinical Trial.

作者信息

Ghanbarian Razieh, Valiani Mahboubeh, Allameh Zahra, Ranjbar Maryam, Mazaheri Mohammad

机构信息

Department of Persian Medicine, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Reproductive Sciences and Sexual Health Research Center, Midwifery and Reproductive Health Department, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Adv Biomed Res. 2024 Sep 23;13:75. doi: 10.4103/abr.abr_111_23. eCollection 2024.

Abstract

BACKGROUND

Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects women of child-bearing age, with a worldwide prevalence ranging from 6 to 20%. Considering the potential side effects of chemical medications and the need for long-term drug administration, complementary treatments such as acupuncture, auriculotherapy, and herbal medicine have been considered. Hence, this study was designed to compare the effects of auriculotherapy, a herbal component (Aslagh capsule), and metformin on the clinical symptoms of PCOS.

MATERIALS AND METHODS

This is a randomized controlled clinical trial study, which allocated 24 women, aged 18-43 years old, with oligomenorrhea in PCOs, in a 1:1:1 ratio, to three groups.

RESULT

A decreasing pattern in the duration of the menstrual cycle was observed in all three groups, but this was significant only in the auriculotherapy group. There were no significant differences between the three groups in acne and hirsutism scores. However, there was a significant reduction in excess hair growth and density of hair in the auriculotherapy group compared to the other two groups ( < 0.05). Besides, in the auriculotherapy group, the reduction in thickness of excess hair at the end of the second and third months of treatment were marginally significant compared to the two other groups.

CONCLUSIONS

Auriculotherapy and Aslagh capsule can be effective in reducing PCOS symptoms, similar to metformin. However, auriculotherapy is more effective than the other treatments in reducing the duration of the menstrual cycle, excess hair growth, and hair density.

摘要

背景

多囊卵巢综合征(PCOS)是一种影响育龄女性的内分泌疾病,在全球范围内的患病率为6%至20%。考虑到化学药物的潜在副作用以及长期用药的需求,人们开始考虑使用针灸、耳穴疗法和草药等辅助治疗方法。因此,本研究旨在比较耳穴疗法、一种草药成分(阿斯莱格胶囊)和二甲双胍对PCOS临床症状的影响。

材料与方法

这是一项随机对照临床试验研究,将24名年龄在18 - 43岁、患有多囊卵巢综合征且月经稀发的女性按1:1:1的比例分为三组。

结果

三组患者的月经周期持续时间均呈下降趋势,但仅耳穴疗法组有显著差异。三组在痤疮和多毛评分方面无显著差异。然而,与其他两组相比,耳穴疗法组的多余毛发增长和毛发密度有显著降低(<0.05)。此外,在耳穴疗法组中,治疗第二个月和第三个月末多余毛发厚度的降低与其他两组相比略有显著差异。

结论

耳穴疗法和阿斯莱格胶囊在减轻PCOS症状方面可能与二甲双胍同样有效。然而,耳穴疗法在缩短月经周期持续时间、减少多余毛发增长和毛发密度方面比其他治疗方法更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c8e/11542685/9f0f2e36efba/ABR-13-75-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验