Zhou X, Liu Z Q, Li W, Wang Z M
Department of Stomatology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2019 Mar 9;54(3):151-156. doi: 10.3760/cma.j.issn.1002-0098.2019.03.002.
To evaluate the effects of periodontal therapy on the quality of life in chronic obstructive pulmonary disease (COPD) patients with chronic periodontitis (CP). In a randomized controlled pilot study, 60 COPD patients with CP were randomly assigned into three groups to receive scaling and root planing (SRP) treatment, supragingival scaling treatment and oral hygiene instructions only with no periodontal treatment, respectively. The scores of each patient's quality of life at baseline, 1 year and 2 years, respectively, were evaluated by using the standardized St George's respiratory questionnaire (SGRQ). The SGRQ was composed of three dimensions: symptoms, activity, and impact. A score was calculated for each section and a total summary score was also calculated. A high score indicated poor health and a decrease in the score indicates an improvement in quality of life. There were no statistically significant differences among the three groups for age, gender, body mass index, smoking status, lung funtion, periodontal parameters and the SGRQ scores (including total, symptoms, activity and impacts scores) among three groups at baseline (all 0.05). The SGRQ scores were all significantly correlated with major lung function parameters (=-0.54 --0.28). The result of ANCOVA analysis adjusted for the influence of baseline measurements showed that the total scores of two periodontal treatment groups were significantly lower (0.01) than that of control group at 2-year follow-up (SRP group: 31.1±12.1; scaling group: 28.9±9.8; control group: 46.5±24.9). The symptoms score of SRP group (45.4±19.7) was significantly lower (0.03) than that of control group (53.6±25.4) at 2-year follow-up. The impacts scores of two treatment groups were significantly lower (0.02) than that of control group at 2-year follow-up (SRP group: 15.2±8.3; scaling group: 14.9±7.7; control group: 34.8±18.8). Our preliminary results from this study suggest that non-surgical periodontal treatment in COPD patients with CP might improve the quality of life of the COPD patient.
评估牙周治疗对慢性阻塞性肺疾病（COPD）合并慢性牙周炎（CP）患者生活质量的影响。在一项随机对照试验性研究中，60例COPD合并CP的患者被随机分为三组，分别接受龈下刮治和根面平整（SRP）治疗、龈上洁治治疗以及仅接受口腔卫生指导而不进行牙周治疗。分别在基线、1年和2年时，使用标准化的圣乔治呼吸问卷（SGRQ）评估每位患者的生活质量得分。SGRQ由症状、活动和影响三个维度组成。计算每个部分的得分以及总分。高分表明健康状况差，得分降低表明生活质量改善。三组在年龄、性别、体重指数、吸烟状况、肺功能、牙周参数以及基线时三组的SGRQ得分（包括总分、症状、活动和影响得分）方面均无统计学显著差异（均P>0.05）。SGRQ得分与主要肺功能参数均显著相关（r=-0.54至-0.28）。经协方差分析调整基线测量影响后的结果显示，在2年随访时，两个牙周治疗组的总分均显著低于对照组（P<0.01）（SRP组：31.1±12.1；洁治组：28.9±9.8；对照组：46.5±24.9）。在2年随访时，SRP组的症状得分（45.4±19.7）显著低于对照组（53.6±25.4）（P<0.03）。在2年随访时，两个治疗组的影响得分均显著低于对照组（P<0.02）（SRP组：15.2±8.3；洁治组：14.9±7.7；对照组：34.8±18.8）。本研究的初步结果表明，COPD合并CP患者的非手术牙周治疗可能改善COPD患者的生活质量。
