Department of Stomatology, Beijing ChaoYang Hospital affiliated to Capital Medical University, Beijing, China.
Respir Med. 2011 Jan;105(1):67-73. doi: 10.1016/j.rmed.2010.06.017. Epub 2010 Jul 13.
To evaluate the association of periodontal health and parameters of quality of life assessed in 306 Chinese patients with chronic obstructive pulmonary disease (COPD).
Periodontal status and respiratory function in 306 COPD patients were clinically evaluated and their quality of life was assessed using the standardized St George's Respiratory Questionnaire (SGRQ).
The SGRQ scores were all significantly correlated with major lung function parameters (r(2) = -0.37 to -0.28; all p < 0.0001) and Medical Research Council dyspnoea scale (r(2) = 0.23 to 0.30; all p < 0.0001). The SGRQ scores also correlated with the 6-min walk test (r(2) = -0.15 to -0.13; all p < 0.05). Of periodontal health parameters, missing tooth number and plaque index appeared to be related to the scores of quality of life. The age- and gender-adjusted Pearson's correlation coefficients between missing teeth and total score, symptoms score, and activity score were 0.09, 0.12, and 0.12, respectively (all p < 0.05). The Pearson's correlation coefficients between plaque index and symptoms score and activity score were 0.09 and 0.09 (p < 0.05). After adjusting for age, gender, body mass index, and smoking status, missing teeth remained significantly associated with symptom score (p = 0.030) and activity score (p = 0.033) while plaque index was significantly associated with symptom score (p = 0.007).
Poor periodontal health as reflected by missing teeth and plaque index was significantly associated with lower quality of life in COPD patients. Our findings indicate the importance of promoting dental care in current public health strategies to improve the quality of life in COPD patients.
评估牙周健康状况与 306 例中国慢性阻塞性肺疾病（COPD）患者生活质量评估参数之间的相关性。
对 306 例 COPD 患者的牙周状况和呼吸功能进行临床评估，并使用标准化的圣乔治呼吸问卷（SGRQ）评估其生活质量。
SGRQ 评分与主要肺功能参数（r²= -0.37 至-0.28；均 p<0.0001）和医学研究委员会呼吸困难量表（r²= 0.23 至 0.30；均 p<0.0001）均呈显著相关。SGRQ 评分还与 6 分钟步行试验（r²= -0.15 至-0.13；均 p<0.05）相关。在牙周健康参数中，失牙数和菌斑指数似乎与生活质量评分相关。失牙数与总评分、症状评分和活动评分的年龄和性别校正 Pearson 相关系数分别为 0.09、0.12 和 0.12（均 p<0.05）。菌斑指数与症状评分和活动评分的 Pearson 相关系数分别为 0.09 和 0.09（p<0.05）。在校正年龄、性别、体重指数和吸烟状况后，失牙数与症状评分（p=0.030）和活动评分（p=0.033）仍显著相关，而菌斑指数与症状评分显著相关（p=0.007）。
缺失牙和菌斑指数反映的牙周健康状况较差与 COPD 患者的生活质量较低显著相关。我们的研究结果表明，在当前的公共卫生策略中，促进口腔保健对于提高 COPD 患者的生活质量非常重要。
