Department of Pharmaceutical Microbiology, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
Department of Microbiology, Nanjing Institute of Fisheries Science, Nanjing 210036, China.
Mar Drugs. 2019 Mar 8;17(3):161. doi: 10.3390/md17030161.
Carotenoids are natural pigments found in plants and microorganisms. These important nutrients play significant roles in animal health. In contrast to plant production, the advantages of microbial fermentation of carotenoids are the lower media costs, fast growth rate of microorganisms, and the ease of culture condition control. In this study, a colony of red pigment-producing yeast, sp. RY1801, was isolated from the sediment of marine environment with the potential to produce carotenoids. Optimization of carotenoid production in sp. RY1801 was also discussed. The optimum conditions found for carotenoid production were as follows: temperature, 28 °C; pH 5.0; carbon source, 10 g/L glucose, nitrogen source, 10 g/L yeast extract, maximum concentration of 987 µg/L of total carotenoids was obtained. The results of this study show that the isolated yeast strain sp. RY1801 can potentially be used in future as a promising microorganism for the commercial production of carotenoids.
类胡萝卜素是存在于植物和微生物中的天然色素。这些重要的营养物质在动物健康中起着重要作用。与植物生产相比，微生物发酵类胡萝卜素的优势在于培养基成本较低、微生物生长速度快，以及易于控制培养条件。在这项研究中，从海洋环境沉积物中分离出一株红色素产生酵母， sp. RY1801，具有产生类胡萝卜素的潜力。还讨论了 sp. RY1801 中类胡萝卜素生产的优化。发现类胡萝卜素生产的最佳条件如下：温度，28°C；pH 值 5.0；碳源，10 g/L 葡萄糖，氮源，10 g/L 酵母提取物，总类胡萝卜素的最高浓度为 987 µg/L。本研究结果表明，分离出的酵母菌株 sp. RY1801 有望在未来作为一种有前途的微生物，用于商业化生产类胡萝卜素。
