Department of Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins Asthma and Allergy Center, Johns Hopkins University, Baltimore, Md.
Department of Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins Asthma and Allergy Center, Johns Hopkins University, Baltimore, Md.
J Allergy Clin Immunol. 2019 Jul;144(1):312-315.e1. doi: 10.1016/j.jaci.2019.03.001. Epub 2019 Mar 9.
Using novel co-culture model systems, galectin-3 is shown to facilitate basophil secretion of IL-4/IL-13, with implications that this unique mode of activation may be linked to a variety of diseases ranging from asthma to cancer.
使用新型共培养模型系统表明，半乳糖凝集素-3 可促进嗜碱性粒细胞分泌 IL-4/IL-13，这意味着这种独特的激活方式可能与从哮喘到癌症等各种疾病有关。
