Department of Urology, Herlev and Gentofte Hospital, Herlev, Denmark.
Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy; Università Vita-Salute San Raffaele, Milan, Italy.
Eur Urol Focus. 2019 Jul;5(4):539-544. doi: 10.1016/j.euf.2019.02.021. Epub 2019 Mar 8.
Men with low serum testosterone and symptoms of androgen deficiency may be diagnosed with testosterone deficiency. This condition is associated with metabolic syndrome and cardiovascular disease. The benefits (eg, improvement in sexual function) and risks (eg, prostate cancer and cardiovascular disease) of testosterone therapy are controversial. The American Urological Association and European Association of Urology guidelines on testosterone therapy differ on several points of management, likely reflecting the ambiguities surrounding testosterone therapy in practice. This paper summarizes both guidelines with a focus on the differences between the two sets of guidelines. PATIENT SUMMARY: The benefits and risks of testosterone therapy are controversial, as reflected in the European Association of Urology and American Urological Association guidelines that differ on several points of management.
患有低血清睾丸酮和雄激素缺乏症状的男性可能被诊断为睾丸酮缺乏症。这种情况与代谢综合征和心血管疾病有关。睾丸激素治疗的益处（如性功能改善）和风险（如前列腺癌和心血管疾病）存在争议。美国泌尿外科学会和欧洲泌尿外科学会的睾丸激素治疗指南在管理的几个方面存在差异，这可能反映了睾丸激素治疗在实践中存在的模糊性。本文总结了这两份指南，重点介绍了这两份指南之间的差异。患者总结：欧洲泌尿外科学会和美国泌尿外科学会的指南在睾丸激素治疗的几个管理要点上存在差异，这反映了睾丸激素治疗的益处和风险存在争议。
