Department of Cardiac Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Department of Cardiac Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Semin Thorac Cardiovasc Surg. 2019 Winter;31(4):852-854. doi: 10.1053/j.semtcvs.2019.03.001. Epub 2019 Mar 8.
Autologous pericardium, fixed in glutaraldehyde, is a common patch material used in heart valve reconstruction. Competence of a reconstructed valve depends on patch dimensions and also on how much the patch deforms when the closed valve is pressurized. In this study, we used biaxial testing to evaluate the deformability of fixed autologous pericardium, and several commercial alternatives, under typical cardiac loads. We found that deformability of fixed autologous pericardium varies predictably with fixation time. This information can be used by surgeons in designing patches for valve repair.
戊二醛固定的自体心包是心脏瓣膜重建中常用的补片材料。重建瓣膜的功能取决于补片的尺寸以及在关闭的瓣膜受压时补片的变形程度。在这项研究中，我们使用双轴测试评估了固定的自体心包和几种商业替代品在典型心脏负荷下的可变形性。我们发现固定的自体心包的可变形性随固定时间的变化而可预测。这些信息可被外科医生用于设计瓣膜修复的补片。
