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营养和药理学干预促进老年人肌肉损伤运动后的恢复:文献综述

Nutritional and Pharmacological Interventions to Expedite Recovery Following Muscle-Damaging Exercise in Older Adults: A Narrative Review of the Literature.

作者信息

Clifford Tom

出版信息

J Aging Phys Act. 2019 Dec 1;27(4):914-928. doi: 10.1123/japa.2018-0351.

DOI:10.1123/japa.2018-0351
PMID:30859892
Abstract

Exercise-induced muscle damage (EIMD) manifests as muscle soreness, inflammation, and reductions in force generating capacity that can last for several days after exercise. The ability to recover and repair damaged tissues following EIMD is impaired with age, with older adults (≥50 years old) experiencing a slower rate of recovery than their younger counterparts do for the equivalent exercise bout. This narrative review discusses the literature examining the effect of nutritional or pharmacological supplements taken to counter the potentially debilitating effects of EIMD in older adults. Studies have assessed the effects of nonsteroidal anti-inflammatory drugs, vitamin C and/or E, or higher protein diets on recovery in older adults. Each intervention showed some promise for attenuating EIMD, but, overall, there is a paucity of available data in this population, and more studies are required to determine the influence of nutrition or pharmacological interventions on EIMD in older adults.

摘要

运动诱导的肌肉损伤(EIMD)表现为肌肉酸痛、炎症以及力量生成能力下降,这些症状在运动后可持续数天。随着年龄增长,EIMD后受损组织的恢复和修复能力会受到损害,老年人(≥50岁)在同等运动强度下的恢复速度比年轻人慢。这篇叙述性综述讨论了相关文献,这些文献研究了营养或药物补充剂对减轻老年人EIMD潜在衰弱影响的作用。研究评估了非甾体抗炎药、维生素C和/或E,或高蛋白饮食对老年人恢复的影响。每种干预措施在减轻EIMD方面都显示出了一些希望,但总体而言,该人群中可用数据较少,需要更多研究来确定营养或药物干预对老年人EIMD的影响。

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