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洛杉矶年轻成年医用大麻患者和非患者使用者中的非法药物使用和处方药物滥用。

Illicit drug use and prescription drug misuse among young adult medical cannabis patients and non-patient users in Los Angeles.

机构信息

Department of Community Health and Prevention, Dornsife School of Public Health, Drexel University, 3215 Market Street, Philadelphia, PA 19104, United States.

Department of Research and Sponsored Programs, California State University Northridge, University Hall 275, 18111 Nordhoff Street, Northridge, CA 91330-8222, United States.

出版信息

Drug Alcohol Depend. 2019 May 1;198:21-27. doi: 10.1016/j.drugalcdep.2019.01.026. Epub 2019 Feb 27.

Abstract

INTRODUCTION

Young adults have the highest rates of cannabis and other drug use, as compared to other age groups, and contribute a significant proportion to the total population of medical cannabis patients (MCP). However, little is known about the relationships between various cannabis practices and illicit drug use/prescription drug misuse among young adult cannabis users with and without legal access to medical cannabis.

METHODS

210 MCP and 156 non-patient cannabis users (NPU) aged 18-26 were recruited in Los Angeles in 2014-15 for a longitudinal study assessing the impact of medical cannabis on health and substance use among emerging adults. For the present analysis, only quantitative baseline survey data were used. Logistic regression was used to examine the associations between past 90-day cannabis practices and other drug use, including illicit drug use and prescription drug misuse.

RESULTS

Illicit drug use was associated with being non-Hispanic white (AOR = 3.0, 95% CI 1.8-5.1), use of cannabis concentrates (AOR = 2.8, 95% CI 1.6-4.9), while self-reported medical cannabis use was associated with lower probability of illicit drug use (AOR = 0.5, 95% CI 0.3-0.9). The odds of prescription drug misuse were increased for participants who reported use of cannabis edibles (AOR = 2.0, 95% CI 1.1-3.5), and decreased with age (AOR = 0.9, 95% CI 0.8-1.0) and for those who used cannabis alone (AOR = 0.5, 95% CI 0.3-0.9).

CONCLUSION

Use of alternative cannabis forms, but not cannabis use frequency, were associated with greater odds of other drug use. Self-reported medical cannabis use, but not MCP status, decreased probability of illicit drug use.

摘要

简介

与其他年龄组相比,年轻人的大麻和其他药物使用率最高,占医疗大麻患者(MCP)总人口的很大比例。然而,对于有和没有合法获得医疗大麻途径的年轻成年大麻使用者中,各种大麻使用方式与非法药物使用/处方药物滥用之间的关系知之甚少。

方法

2014 年至 2015 年,在洛杉矶招募了 210 名 MCP 和 156 名非患者大麻使用者(NPU),年龄在 18-26 岁之间,进行了一项纵向研究,评估医疗大麻对成年初期健康和物质使用的影响。对于本分析,仅使用了定量基线调查数据。使用逻辑回归检查过去 90 天的大麻使用方式与其他药物使用(包括非法药物使用和处方药物滥用)之间的关联。

结果

与非西班牙裔白人(AOR=3.0,95%CI 1.8-5.1)、使用大麻浓缩物(AOR=2.8,95%CI 1.6-4.9)相关的非法药物使用,而自我报告的医疗大麻使用与非法药物使用的可能性降低有关(AOR=0.5,95%CI 0.3-0.9)。报告使用大麻食用品(AOR=2.0,95%CI 1.1-3.5)的参与者,处方药物滥用的几率增加,而随着年龄(AOR=0.9,95%CI 0.8-1.0)和单独使用大麻(AOR=0.5,95%CI 0.3-0.9)而减少。

结论

使用替代大麻形式,而不是大麻使用频率,与其他药物使用的几率增加有关。自我报告的医疗大麻使用,但不是 MCP 状态,降低了非法药物使用的可能性。

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