School of Medicine and Public Health, The University of Newcastle, University Drive, Callaghan, Australia.
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
J Ment Health. 2021 Feb;30(1):12-19. doi: 10.1080/09638237.2019.1581354. Epub 2019 Mar 12.
Although post-traumatic stress disorder (PTSD) often co-occurs with depression and alcohol use disorder (AUD), treatment settings may not screen for PTSD symptoms.
To explore the effects of PTSD symptoms in participants seeking treatment for depression and alcohol misuse by capitalising on the DAISI (Depression and Alcohol Integrated and Single focussed Interventions) project.
Participants ( = 220) with current depressive symptoms and alcohol misuse were recruited from the DAISI project, a randomised controlled trial with four treatment arms. PTSD symptoms were assessed at baseline by the Posttraumatic Stress Diagnostic Scale and again at the 3-month assessment.
McNemars -test assessed for changes in PTSD symptom severity and PTSD symptom clusters at the 3-month assessment. Repeated measures multivariate analysis of variance assessed for changes in PTSD symptoms, by DAISI treatment allocation. At the 3-month assessment, participants with PTSD reported significant reductions in PTSD symptoms (except intrusion) and a lower rate of PTSD, and responded better to integrated depression-alcohol misuse CBT than to the alcohol/depression single-focussed or brief interventions.
Integrated depression and alcohol misuse CBT may be effective for PTSD symptoms, but intrusions may need to be addressed specifically.
尽管创伤后应激障碍（PTSD）常与抑郁和酒精使用障碍（AUD）共病，但治疗场所可能不会对 PTSD 症状进行筛查。
利用 DAISI（抑郁和酒精综合与单一焦点干预）项目，探讨 PTSD 症状对寻求抑郁和酒精滥用治疗的参与者的影响。
从 DAISI 项目中招募了当前有抑郁症状和酒精滥用的参与者（ = 220），该项目是一个具有四个治疗组的随机对照试验。使用创伤后应激障碍诊断量表在基线和 3 个月评估时评估 PTSD 症状。
McNemar 检验评估了 PTSD 症状严重程度和 PTSD 症状群在 3 个月评估时的变化。重复测量多元方差分析评估了 PTSD 症状随 DAISI 治疗分配的变化。在 3 个月评估时，患有 PTSD 的参与者报告 PTSD 症状（除了侵入）显著减轻，PTSD 发生率较低，对综合抑郁-酒精滥用认知行为疗法的反应优于酒精/抑郁单一焦点或简短干预。
综合抑郁和酒精滥用认知行为疗法可能对 PTSD 症状有效，但可能需要专门解决侵入问题。
