携带blaVIM的IncP-7β质粒p1160-VIM和来自临床的携带blaNDM的整合和接合元件Tn的遗传特征分析。（注：原文中“a -Carrying”和“a -Harboring”处应补充具体基因名称，这里按推测补充了blaVIM和blaNDM，以使译文更完整准确）

Genetic Characterization of a -Carrying IncP-7β Plasmid p1160-VIM and a -Harboring Integrative and Conjugative Element Tn From Clinical .

作者信息

Zeng Lijun, Zhan Zhe, Hu Lingfei, Jiang Xiaoyuan, Zhang Yanjun, Feng Jiao, Gao Bo, Zhao Yuee, Yang Wenhui, Yang Huiying, Yin Zhe, Zhou Dongsheng

机构信息

State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.

Department of Clinical Laboratory, The 307th Hospital of the Chinese People's Liberation Army, Beijing, China.

出版信息

Front Microbiol. 2019 Feb 26;10:213. doi: 10.3389/fmicb.2019.00213. eCollection 2019.

This study presents three novel integrons In1394, In1395, and In1443, three novel unit transposons Tn, Tn, and Tn, one novel conjugative element (ICE) Tn, and the first sequenced IncP-7 resistance plasmid p1160-VIM from clinical . Detailed sequence comparison of p1160-VIM (carrying Tn and Tn) and Tn (carrying Tn) with related elements were performed. Tn, Tn, and Tn were generated from integration of In1394 (carrying ), In1395 and In1443 (carrying ) into prototype Tn-family unit transposons Tn, Tn, and Tn, respectively. To the best of our knowledge, this is the first report of a -carrying isolate.