Ashley K C, Myerthall D L
J Clin Hosp Pharm. 1986 Apr;11(2):95-100. doi: 10.1111/j.1365-2710.1986.tb00832.x.
The susceptibility of 1,000 recent bacterial isolates to noxythiolin was determined by the disc susceptibility method. No Gram-positive strains were resistant to this method but 56 (5.6%) of Gram-negative strains gave zones of inhibition of 12 mm diameter or less. The minimum inhibitory concentration (MIC) of the latter were determined by the agar incorporation method. No strains had MIC values greater than 4096 mg/litre. Since concentrations of 50,000 mg/litre can be used for topical treatment, these organisms may be considered susceptible.
采用纸片药敏法测定了1000株近期分离的细菌对硝噻唑啉的敏感性。革兰氏阳性菌株对该方法均不耐药，但56株（5.6%）革兰氏阴性菌株的抑菌圈直径为12毫米或更小。通过琼脂掺入法测定了后者的最低抑菌浓度（MIC）。没有菌株的MIC值大于4096毫克/升。由于局部治疗可使用50000毫克/升的浓度，因此可认为这些细菌是敏感的。
