针对大运动发育迟缓幼儿的每日和每周康复治疗：一项随机临床试验方案（DRIVE研究）
Daily and Weekly Rehabilitation Delivery for Young Children With Gross Motor Delay: A Randomized Clinical Trial Protocol (the DRIVE Study).
作者信息
Ferrante Rachel, Hendershot Sarah, Baranet Kathy, Barbosa Gardenia, Carey Helen, Maitre Nathalie, Lo Warren, Pan Jeff, Heathcock Jill
机构信息
Nationwide Children's Hospital (Drs Ferrante, Hendershot, Baranet, Maitre, and Lo), Columbus, Ohio; The Ohio State University (Drs Barbosa, Pan, and Heathcock), Columbus, Ohio; Kettering College (Dr Carey), Kettering, Ohio.
出版信息
Pediatr Phys Ther. 2019 Apr;31(2):217-224. doi: 10.1097/PEP.0000000000000594.
Abstract
PURPOSE
The proposed project tests the principle that frequency of rehabilitation is an important regulator of therapeutic response in infants.
METHODS
We will randomize 75 infants with cerebral palsy, 6 to 24 months of age and/or Gross Motor Function Classification System levels III to V (higher severity), to determine the short-term and long-term effects of 3 dosing protocols consisting of an identical number of 2-hour sessions of the same motor learning-based therapy applied over a different total number of calendar weeks.
RESULTS AND CONCLUSIONS
The results will inform clinicians, families, and scientists about dosing and will provide needed recommendations for frequency of rehabilitation to optimize motor function and development of young children with cerebral palsy.
摘要
目的
本项目旨在验证康复频率是婴儿治疗反应重要调节因素这一原理。
方法
我们将把75名年龄在6至24个月和/或粗大运动功能分类系统为III至V级（更高严重程度）的脑瘫婴儿随机分组，以确定三种给药方案的短期和长期效果，这三种方案包含相同数量的每次两小时的基于运动学习的治疗课程，且在不同的总日历周数内进行。
结果与结论
研究结果将为临床医生、家庭和科学家提供有关给药的信息，并为优化脑瘫幼儿运动功能和发育的康复频率提供必要建议。
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