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Chasing the "Holy Grail": Modulating Neutrophils in Inflammatory Lung Disease.

作者信息

Summers Charlotte

机构信息

1 Department of Medicine University of Cambridge Cambridge, United Kingdom.

出版信息

Am J Respir Crit Care Med. 2019 Jul 15;200(2):131-132. doi: 10.1164/rccm.201902-0333ED.

DOI:10.1164/rccm.201902-0333ED
PMID:30865833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6635790/
Abstract
摘要

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本文引用的文献

1
IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses .IL4Rα 信号通路阻断低氧中性粒细胞的存活并限制急性肺损伤反应。
Am J Respir Crit Care Med. 2019 Jul 15;200(2):235-246. doi: 10.1164/rccm.201808-1599OC.
2
Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses.脯氨酰羟化酶2失活增强糖原储存并促进过度的嗜中性粒细胞反应。
J Clin Invest. 2017 Sep 1;127(9):3407-3420. doi: 10.1172/JCI90848. Epub 2017 Aug 14.
3
The cyclin-dependent kinase inhibitor AT7519 accelerates neutrophil apoptosis in sepsis-related acute respiratory distress syndrome.细胞周期蛋白依赖性激酶抑制剂AT7519可加速脓毒症相关急性呼吸窘迫综合征中中性粒细胞的凋亡。
Thorax. 2017 Feb;72(2):182-185. doi: 10.1136/thoraxjnl-2016-209229. Epub 2016 Oct 24.
4
Acute Respiratory Distress Syndrome Neutrophils Have a Distinct Phenotype and Are Resistant to Phosphoinositide 3-Kinase Inhibition.急性呼吸窘迫综合征中性粒细胞具有独特表型且对磷脂酰肌醇3激酶抑制具有抗性。
Am J Respir Crit Care Med. 2016 Oct 15;194(8):961-973. doi: 10.1164/rccm.201509-1818OC.
5
Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries.全球 50 个国家重症监护病房急性呼吸窘迫综合征患者的流行病学、治疗模式和死亡率。
JAMA. 2016 Feb 23;315(8):788-800. doi: 10.1001/jama.2016.0291.
6
Functional disability 5 years after acute respiratory distress syndrome.急性呼吸窘迫综合征 5 年后的功能障碍。
N Engl J Med. 2011 Apr 7;364(14):1293-304. doi: 10.1056/NEJMoa1011802.
7
Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils.低氧选择性抑制人中性粒细胞呼吸爆发活性和金黄色葡萄球菌的杀伤作用。
J Immunol. 2011 Jan 1;186(1):453-463. doi: 10.4049/jimmunol.1002213. Epub 2010 Dec 6.
8
Granulocyte/macrophage colony-stimulating factor causes a paradoxical increase in the BH3-only pro-apoptotic protein Bim in human neutrophils.粒细胞/巨噬细胞集落刺激因子导致人中性粒细胞中唯一的 BH3 结构域 pro-apoptotic 蛋白 Bim 的悖论性增加。
Am J Respir Cell Mol Biol. 2011 Jun;44(6):879-87. doi: 10.1165/rcmb.2010-0101OC. Epub 2010 Aug 12.
9
Advances in neutrophil biology: clinical implications.中性粒细胞生物学进展：临床意义
Chest. 2008 Sep;134(3):606-612. doi: 10.1378/chest.08-0422.
10
Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity.缺氧诱导的中性粒细胞存活由HIF-1α依赖性NF-κB活性介导。
J Exp Med. 2005 Jan 3;201(1):105-15. doi: 10.1084/jem.20040624.