Chasing the "Holy Grail": Modulating Neutrophils in Inflammatory Lung Disease.
作者信息
Summers Charlotte
机构信息
1 Department of Medicine University of Cambridge Cambridge, United Kingdom.
出版信息
Am J Respir Crit Care Med. 2019 Jul 15;200(2):131-132. doi: 10.1164/rccm.201902-0333ED.
Abstract
摘要
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Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses.脯氨酰羟化酶2失活增强糖原储存并促进过度的嗜中性粒细胞反应。
J Clin Invest. 2017 Sep 1;127(9):3407-3420. doi: 10.1172/JCI90848. Epub 2017 Aug 14.
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The cyclin-dependent kinase inhibitor AT7519 accelerates neutrophil apoptosis in sepsis-related acute respiratory distress syndrome.细胞周期蛋白依赖性激酶抑制剂AT7519可加速脓毒症相关急性呼吸窘迫综合征中中性粒细胞的凋亡。
Thorax. 2017 Feb;72(2):182-185. doi: 10.1136/thoraxjnl-2016-209229. Epub 2016 Oct 24.
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