Graduate Program in Dentistry, Paulista University.
Dent Mater J. 2019 Jun 1;38(3):411-417. doi: 10.4012/dmj.2018-064. Epub 2019 Mar 13.
To evaluate the mechanical properties (MP) and antimicrobial activity of a glass ionomer cement (GIC) incorporated with an antimicrobial agent from the aerial parts of Dioscorea altissima. MP were: syneresis & imbibition; solubility; elasticity module; surface microhardness and fluoride release, and the anti-Streptococcus mutans (Smut) activity was accessed by microdilution broth assay and 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) analysis. Syneresis & imbibition did not change over time for both groups, but EG showed lower values at days 7th and 30th. The control group (CG)'s and the experimental group (EG)'s weights were similar before the solubility assay, but after seven days, CG exhibited weight gain in comparison to EG. The elasticity module had no significant differences between groups. The CG showed lower surface microhardness compared to the EG. CG and EG had similar behaviors regarding fluoride release. EG showed diminished Streptococcus mutans count in comparison to CG. EG showed similar or better mechanical properties and an improvement in the antibacterial activity than the original cement.
为评估玻璃离子水门汀(GIC)掺入从盾叶薯蓣地上部分获得的抗菌剂后的机械性能(MP)和抗菌活性。MP 包括:收缩和吸液;溶解度;弹性模量;表面显微硬度和氟化物释放,抗变形链球菌(Smut)活性通过微量稀释肉汤测定法和 3-(4,5-二甲基-2-噻唑基)-2,5-二苯基-2H-四唑溴化物(MTT)分析进行评估。两组的收缩和吸液都没有随时间变化,但 EG 在第 7 天和第 30 天的数值较低。在进行溶解度测定之前,CG 和 EG 的重量相似,但七天后,CG 的重量增加了,而 EG 则减少了。两组之间的弹性模量没有显著差异。CG 的表面显微硬度比 EG 低。CG 和 EG 的氟化物释放行为相似。与 CG 相比,EG 中的变形链球菌数量减少。与原始水泥相比,EG 表现出更好的机械性能和抗菌活性。