提高 T2 期胆囊癌的诊断和治疗水平对于改善该疾病的总体预后至关重要。
Improvement in the diagnosis and treatment of T2 gallbladder carcinoma is pivotal to improvement in the overall prognosis for this disease.
机构信息
Department of General Surgery, XinHua Hospital, Shanghai Jiao Tong University.
Department of Oncology, XinHua Hospital, Shanghai Jiao Tong University.
出版信息
Biosci Trends. 2019;13(1):1-9. doi: 10.5582/bst.2019.01039.
Since the American Joint Committee on Cancer (AJCC) subdivided the T2 stage of gallbladder carcinoma (GBC) into T2a and T2b, the diagnosis and treatment of those stages have been a subject of heated discussion and controversy. T2 is a stage of GBC that might be treatable. Based on the extent of lymph node metastasis and distant metastasis, T2 GBC can be classified into various pathological stages such as IIA, IIB, IIIB, and IVB, leading to controversy in clinical settings. This review aims to discuss the effectiveness of and controversies concerning S4b+5 resection, the acceptable extent of lymph node dissection, the timing for treatment of incidental gallbladder cancer, and adjuvant therapy. This review also aims to suggest directions for and recommendations regarding clinical research in the future.
自从美国癌症联合委员会（AJCC）将胆囊癌（GBC）的 T2 期细分为 T2a 和 T2b 以来，这些阶段的诊断和治疗一直是激烈讨论和争议的话题。T2 期 GBC 可能是可以治疗的。根据淋巴结转移和远处转移的范围，T2 GBC 可以分为各种病理阶段，如 IIA、IIB、IIIB 和 IVB，这在临床上引起了争议。本综述旨在讨论 S4b+5 切除术的有效性和争议、淋巴结清扫的可接受范围、偶然发现的胆囊癌治疗时机以及辅助治疗。本综述还旨在就未来的临床研究提出方向和建议。
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