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一名新诊断为快速进展性新月体性免疫球蛋白A肾病的成年患者的尿毒症性全结肠炎

Uremic Pancolitis in an Adult Patient with Newly Diagnosed, Rapidly Progressive Crescentic Immunoglobulin A Nephropathy.

作者信息

Gonzalez Hector H, McMahon Meaghan, Sanchez Angel E, Foster Jennifer G, Lazar Ira

机构信息

Internal Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.

Miscellaneous, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.

出版信息

Cureus. 2019 Jan 4;11(1):e3826. doi: 10.7759/cureus.3826.

Abstract

Uremic gastroenteropathy is a well-accepted but less often described sequelae of an underlying renal disease. With the advent of modern dialysis treatments, rarer manifestations, such as pancolitis, may go overlooked in the evaluation, pursuing more common diagnoses. The underlying pathophysiology of uremic gastroenteropathy is not completely understood; however, several underlying mechanisms have been identified to play a role. Here, we present an exceptionally rare case of uremic pancolitis in a Hispanic male who presented with clinical, imaging, and pathological findings consistent with newly diagnosed, rapidly progressive crescentic IgA nephropathy (IgAN).

摘要

尿毒症性胃肠病是一种公认但较少被描述的潜在肾脏疾病的后遗症。随着现代透析治疗的出现,在评估过程中可能会忽略一些罕见的表现,如全结肠炎,而更倾向于诊断更常见的疾病。尿毒症性胃肠病的潜在病理生理学尚未完全明确;然而,已确定有几种潜在机制在其中发挥作用。在此,我们报告一例极为罕见的西班牙裔男性尿毒症性全结肠炎病例,其临床、影像学及病理表现均符合新诊断的、快速进展的新月体性IgA肾病(IgAN)。

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