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一名新诊断为快速进展性新月体性免疫球蛋白A肾病的成年患者的尿毒症性全结肠炎

Uremic Pancolitis in an Adult Patient with Newly Diagnosed, Rapidly Progressive Crescentic Immunoglobulin A Nephropathy.

作者信息

Gonzalez Hector H, McMahon Meaghan, Sanchez Angel E, Foster Jennifer G, Lazar Ira

机构信息

Internal Medicine, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.

Miscellaneous, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, USA.

出版信息

Cureus. 2019 Jan 4;11(1):e3826. doi: 10.7759/cureus.3826.

DOI:10.7759/cureus.3826
PMID:30868039
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6402858/
Abstract

Uremic gastroenteropathy is a well-accepted but less often described sequelae of an underlying renal disease. With the advent of modern dialysis treatments, rarer manifestations, such as pancolitis, may go overlooked in the evaluation, pursuing more common diagnoses. The underlying pathophysiology of uremic gastroenteropathy is not completely understood; however, several underlying mechanisms have been identified to play a role. Here, we present an exceptionally rare case of uremic pancolitis in a Hispanic male who presented with clinical, imaging, and pathological findings consistent with newly diagnosed, rapidly progressive crescentic IgA nephropathy (IgAN).

摘要

尿毒症性胃肠病是一种公认但较少被描述的潜在肾脏疾病的后遗症。随着现代透析治疗的出现,在评估过程中可能会忽略一些罕见的表现,如全结肠炎,而更倾向于诊断更常见的疾病。尿毒症性胃肠病的潜在病理生理学尚未完全明确;然而,已确定有几种潜在机制在其中发挥作用。在此,我们报告一例极为罕见的西班牙裔男性尿毒症性全结肠炎病例,其临床、影像学及病理表现均符合新诊断的、快速进展的新月体性IgA肾病(IgAN)。

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本文引用的文献

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TESTING Corticosteroids in IgA Nephropathy: A Continuing Challenge.IgA 肾病中皮质类固醇的试验:一项持续的挑战。
Clin J Am Soc Nephrol. 2018 Jan 6;13(1):158-160. doi: 10.2215/CJN.10560917. Epub 2017 Dec 13.
2
Effect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial.口服甲泼尼龙对IgA肾病患者临床结局的影响:TESTING随机临床试验
JAMA. 2017 Aug 1;318(5):432-442. doi: 10.1001/jama.2017.9362.
3
Role of the Gut Microbiome in Uremia: A Potential Therapeutic Target.
肠道微生物群在尿毒症中的作用:一个潜在的治疗靶点。
Am J Kidney Dis. 2016 Mar;67(3):483-98. doi: 10.1053/j.ajkd.2015.09.027. Epub 2015 Nov 15.
4
Rapidly progressive IgA nephropathy: a form of vasculitis or a complement-mediated disease?快速进展性IgA肾病:一种血管炎形式还是补体介导的疾病?
Clin Kidney J. 2015 Oct;8(5):477-81. doi: 10.1093/ckj/sfv095. Epub 2015 Sep 24.
5
Altered intestinal microbial flora and impaired epithelial barrier structure and function in CKD: the nature, mechanisms, consequences and potential treatment.慢性肾脏病中肠道微生物菌群改变和肠上皮屏障结构与功能障碍:性质、机制、后果和潜在治疗。
Nephrol Dial Transplant. 2016 May;31(5):737-46. doi: 10.1093/ndt/gfv095. Epub 2015 Apr 16.
6
Role of Nrf2 dysfunction in uremia-associated intestinal inflammation and epithelial barrier disruption.Nrf2功能障碍在尿毒症相关肠道炎症和上皮屏障破坏中的作用。
Dig Dis Sci. 2015 May;60(5):1215-22. doi: 10.1007/s10620-014-3428-4. Epub 2014 Nov 16.
7
A case of rapidly progressive IgA nephropathy in a patient with exacerbation of Crohn's disease.一例伴有克罗恩病恶化的快速进展性 IgA 肾病。
BMC Nephrol. 2012 Aug 6;13:84. doi: 10.1186/1471-2369-13-84.
8
The incidence of primary glomerulonephritis worldwide: a systematic review of the literature.原发性肾小球肾炎的全球发病率:文献系统综述。
Nephrol Dial Transplant. 2011 Feb;26(2):414-30. doi: 10.1093/ndt/gfq665. Epub 2010 Nov 10.
9
The spectrum of acute renal failure in IgA nephropathy.IgA 肾病所致急性肾衰竭的谱。
Ren Fail. 2010 May;32(4):428-33. doi: 10.3109/08860221003646345.
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The IgA nephropathy treatment dilemma.IgA肾病的治疗困境。
Kidney Int. 2006 Jun;69(11):1939-44. doi: 10.1038/sj.ki.5000434.