交联催化发夹组装用于活细胞中多种 mRNA 的高对比度成像。
Crosslinking catalytic hairpin assembly for high-contrast imaging of multiple mRNAs in living cells.
机构信息
Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China.
出版信息
Chem Commun (Camb). 2019 Apr 7;55(27):3899-3902. doi: 10.1039/c9cc01033e. Epub 2019 Mar 14.
PMID:30869692
Abstract
A novel DNA nanotetrad mediated crosslinking catalytic hairpin assembly (CCHA) is reported to generate clumps of cross-linked mesh products for high-contrast and simultaneous imaging of multiple mRNAs in living cells.
摘要
报道了一种新型的 DNA 纳米四联体介导的交联发夹组装（CCHA），用于生成交联网格产物的团簇，以实现活细胞中多个 mRNA 的高对比度和同时成像。
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