Department of Spine Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Department of Radiology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
World Neurosurg. 2019 Jun;126:e901-e906. doi: 10.1016/j.wneu.2019.03.008. Epub 2019 Mar 11.
To investigate effectiveness of brace treatment in patients with adolescent idiopathic scoliosis with curve between 40° and 45° and to determine predictive factors associated with bracing outcome.
Bracing was used to treat 90 patients with curve >40 degrees. Factors including Risser sign, age, sex, curve pattern, curve magnitude, and initial curve correction were compared between patients with curve improvement and patients with curve progression. Logistic regression analysis was used to determine the independent predictors of curve progression.
Curve was improved in 34 (37.8%) patients and stabilized in 12 (13.3%) patients. Remarkable curve progression >50 degrees was observed in 44 (48.9%) patients. Intergroup comparison showed significant differences between the 2 groups in terms of age (12.3 ± 1.4 years vs. 13.2 ± 1.6 years, P = 0.01), initial curve correction (2.2% ± 5.4% vs. 19.7% ± 12.2%, P < 0.001), and curve pattern (P = 0.03). Logistic regression analysis showed that initial curve correction of <10% (odds ratio = 12.82, P < 0.001) and Risser grade of 0 (odds ratio = 1.46, P = 0.04) were significant indicators of curve progression.
Bracing may produce a favorable outcome in certain patients with curve between 40° and 45°. It should be cautiously used in this situation, as there was a higher probability of bracing failure. It is important to differentiate patients at high risk of curve progression at an early stage to avoid overtreatment.
探讨支具治疗 40°-45°青少年特发性脊柱侧凸患者的疗效,并确定与支具治疗结果相关的预测因素。
对 90 例>40 度的患者进行支具治疗。比较两组患者(曲线改善组和曲线进展组)之间的 Risser 征、年龄、性别、曲线类型、曲线幅度和初始曲线矫正等因素。采用 logistic 回归分析确定曲线进展的独立预测因素。
34 例(37.8%)患者的曲线得到改善,12 例(13.3%)患者的曲线稳定。44 例(48.9%)患者出现明显的>50 度的曲线进展。组间比较显示,两组在年龄(12.3±1.4 岁比 13.2±1.6 岁,P=0.01)、初始曲线矫正(2.2%±5.4%比 19.7%±12.2%,P<0.001)和曲线类型(P=0.03)方面存在显著差异。logistic 回归分析显示,初始曲线矫正<10%(比值比=12.82,P<0.001)和 Risser 分级为 0(比值比=1.46,P=0.04)是曲线进展的显著指标。
支具治疗在特定的 40°-45°之间的患者中可能产生良好的结果。在这种情况下应谨慎使用支具,因为支具失败的可能性更高。早期区分高度进展风险的患者以避免过度治疗很重要。