Pusch H H, Pürstner P, Haas J
Andrologia. 1986 Mar-Apr;18(2):201-7. doi: 10.1111/j.1439-0272.1986.tb01763.x.
30 patients with isolated asthenozoospermia received a treatment with 5000 I.U. Human-Chorionic-Gonadotropin (HCG) a week intramuscularly for twelve weeks. Pretreatment basal levels of FSH, LH and testosterone were in normal or low normal range. 16 males responded to therapy, the total motility of spermatozoa increased significantly from 34% to 40%. In spite of a decreased sperm density and morphologic quality 6 pregnancies occurred. This result strengthens the interpretation, that sperm motility is the most important factor for fertilization. HCG therapy must be considered as an additional approach for treating motility disturbances, especially in cases with high sperm densities.
30例单纯弱精子症患者接受了为期12周的治疗，每周肌肉注射5000国际单位人绒毛膜促性腺激素（HCG）。治疗前促卵泡生成素（FSH）、促黄体生成素（LH）和睾酮的基础水平处于正常或略低于正常范围。16名男性对治疗有反应，精子的总活力从34%显著提高到40%。尽管精子密度和形态质量有所下降，但仍有6例妊娠发生。这一结果强化了这样的解释，即精子活力是受精的最重要因素。HCG疗法必须被视为治疗活力障碍的一种额外方法，尤其是在精子密度高的情况下。
