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用于全场光学相干断层扫描的单次波长无关相移方法。

Single-shot wavelength-independent phase-shifting method for full-field optical coherence tomography.

作者信息

Zhu Yue, Gao Wanrong

出版信息

Appl Opt. 2019 Feb 1;58(4):806-813. doi: 10.1364/AO.58.000806.

DOI:10.1364/AO.58.000806
PMID:30874124
Abstract

One limitation of a piezoelectric translator-based phase-shifting method in full-field optical coherence tomography (FF-OCT) is that there exist interference residuals because a light source with broadband is used. In this work, an achromatic phase-shifting method was proposed in which a linear polarizer and a quarter-wave plate were employed to generate the circularly polarized light in the reference arm of a basic Linnik interferometer. The light field reflected from the reference arm is supposed with the unpolarized light backscattered from the sample when the path difference is within the coherence length of the light source. A first phase difference of π/2 can be generated on the propagation of superposed light beams through the polarized beam splitter. An additional phase difference of π/2 can be obtained by the proposed numerical method, thus producing the similar effects as the four-frame phase-shifting way. An en face tomographic image can be obtained with a single-shot in this new FF-OCT system. The axial and lateral resolutions of the system are around 1.4 μm and 0.8 μm, respectively. The system offers a dynamic range of ∼56  dB and an imaging rate of 30 fps. Tomographic images of Intel microchip, onion cells, and microcracks in the glass were displayed with clear substructures. This article aims at producing fringe-free OCT images in a single shot.

摘要

基于压电平移器的相移方法在全场光学相干断层扫描(FF - OCT)中的一个局限性在于,由于使用了宽带光源,存在干涉残余。在这项工作中,提出了一种消色差相移方法,其中在基本林尼克干涉仪的参考臂中采用线性偏振器和四分之一波片来产生圆偏振光。当光程差在光源的相干长度内时,假设参考臂反射的光场与样品背向散射的非偏振光相同。在叠加光束通过偏振分束器传播时可产生π/2的初始相位差。通过所提出的数值方法可获得额外的π/2相位差,从而产生与四帧相移方法类似的效果。在这种新型FF - OCT系统中单次拍摄即可获得面内断层图像。该系统的轴向分辨率和横向分辨率分别约为1.4μm和0.8μm。该系统的动态范围约为56dB,成像速率为30fps。展示了英特尔微芯片、洋葱细胞和玻璃中的微裂纹的断层图像,其亚结构清晰。本文旨在单次拍摄生成无条纹的OCT图像。

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引用本文的文献

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Fractal-based aberration-corrected full-field OCT.基于分形的像差校正全场光学相干断层扫描
Biomed Opt Express. 2023 Jun 27;14(7):3775-3797. doi: 10.1364/BOE.485090. eCollection 2023 Jul 1.
2
Methods and applications of full-field optical coherence tomography: a review.全场光学相干断层扫描方法与应用:综述。
J Biomed Opt. 2022 May;27(5). doi: 10.1117/1.JBO.27.5.050901.