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本文引用的文献

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Correlates of viral suppression among HIV-infected men who have sex with men and transgender women in Lima, Peru.秘鲁利马男男性行为者及变性女性中艾滋病毒感染者病毒抑制的相关因素。
AIDS Care. 2018 Nov;30(11):1341-1350. doi: 10.1080/09540121.2018.1476657. Epub 2018 May 30.
2
Peruvian Mental Health Reform: A Framework for Scaling-up Mental Health Services.秘鲁精神卫生改革:扩大精神卫生服务规模的框架。
Int J Health Policy Manag. 2017 Sep 1;6(9):501-508. doi: 10.15171/ijhpm.2017.07.
3
Factors associated with previously undiagnosed human immunodeficiency virus infection in a population of men who have sex with men and male-to-female transgender women in Lima, Peru.秘鲁利马男男性行为者及男变女跨性别女性群体中与既往未诊断出的人类免疫缺陷病毒感染相关的因素。
Medicine (Baltimore). 2016 Oct;95(42):e5147. doi: 10.1097/MD.0000000000005147.
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Adherence to Antiretroviral Therapy During and After Pregnancy: Cohort Study on Women Receiving Care in Malawi's Option B+ Program.马拉维“B+方案”中接受护理的女性在孕期及产后对抗逆转录病毒疗法的依从性:队列研究
Clin Infect Dis. 2016 Nov 1;63(9):1227-1235. doi: 10.1093/cid/ciw500. Epub 2016 Jul 26.
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HIV prevention among transgender women in Latin America: implementation, gaps and challenges.拉丁美洲跨性别女性中的艾滋病预防:实施情况、差距与挑战。
J Int AIDS Soc. 2016 Jul 17;19(3 Suppl 2):20799. doi: 10.7448/IAS.19.3.20799. eCollection 2016.
6
How Peru introduced a plan for comprehensive HIV prevention and care for transwomen.秘鲁如何推出一项针对跨性别女性的全面艾滋病毒预防和护理计划。
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Integrated and Gender-Affirming Transgender Clinical Care and Research.综合且肯定性别的跨性别临床护理与研究
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8
Global health burden and needs of transgender populations: a review.跨性别群体的全球健康负担与需求:一项综述
Lancet. 2016 Jul 23;388(10042):412-436. doi: 10.1016/S0140-6736(16)00684-X. Epub 2016 Jun 17.
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Peru's HIV care continuum among men who have sex with men and transgender women: opportunities to optimize treatment and prevention.秘鲁男男性行为者和跨性别女性中的艾滋病毒治疗连续过程:优化治疗与预防的机会
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HIV Prevalence and Risks Associated with HIV Infection among Transgender Individuals in Cambodia.柬埔寨变性者中艾滋病毒的流行情况及与艾滋病毒感染相关的风险
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秘鲁利马的跨性别女性中与 HIV 病毒抑制相关的因素。

Factors Associated with HIV Viral Suppression Among Transgender Women in Lima, Peru.

机构信息

1 AIDS Program, Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut.

2 Centre of Excellence for Research in AIDS (CERiA), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

LGBT Health. 2018 Nov/Dec;5(8):477-483. doi: 10.1089/lgbt.2017.0186.

DOI:10.1089/lgbt.2017.0186
PMID:30874476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6306649/
Abstract

PURPOSE

Globally, transgender women (TGW) experience a high burden of adverse health outcomes, including a high prevalence of HIV and sexually transmitted infections (STIs) as well as psychiatric disorders and substance use disorders. To address gaps in HIV research in Peru focused specifically on TGW, this study presents characteristics of a sample of HIV-positive TGW and identifies factors associated with viral suppression.

METHODS

Between June 2015 and August 2016, 50 HIV-positive TGW were recruited in Lima, Peru. Multivariable logistic regression was used to identify factors associated with viral suppression (<200 copies/mL) among the TGW.

RESULTS

Among TGW, 85% achieved viral suppression. Approximately half (54%) reported anal sex with more than five partners in the past 6 months, 38% reported sex work, 68% had not disclosed their HIV status to one or more of their partners, and 38% reported condomless sex with their last partner. The prevalence of alcohol use disorders was high (54%), and 38% reported use of drugs in the past year. Moderate-to-severe drug use significantly reduced odds of achieving viral suppression (adjusted odds ratio 0.69; 95% confidence interval: 0.48-0.98).

CONCLUSION

Our findings highlight the need for integrated treatment for substance disorders in HIV care to increase the viral suppression rate among TGW in Lima, Peru.

摘要

目的

在全球范围内,跨性别女性(TGW)面临着沉重的健康问题负担,包括 HIV 和性传播感染(STI)的高发率,以及精神障碍和物质使用障碍。为了解决秘鲁在 HIV 研究方面针对 TGW 的空白,本研究介绍了一组 HIV 阳性 TGW 的特征,并确定了与病毒抑制相关的因素。

方法

在 2015 年 6 月至 2016 年 8 月期间,在秘鲁利马招募了 50 名 HIV 阳性 TGW。采用多变量逻辑回归分析确定了与 TGW 病毒抑制(<200 拷贝/ml)相关的因素。

结果

在 TGW 中,85%的人实现了病毒抑制。约一半(54%)报告在过去 6 个月内与超过 5 名性伴侣发生过肛交,38%报告从事性工作,68%未向一个或多个性伴侣透露其 HIV 状况,38%报告与最近的性伴侣发生过无保护性行为。酒精使用障碍的患病率很高(54%),38%报告在过去一年中使用过毒品。中度至重度药物使用显著降低了实现病毒抑制的几率(调整后的优势比为 0.69;95%置信区间:0.48-0.98)。

结论

我们的研究结果强调了在 HIV 护理中需要综合治疗物质障碍,以提高秘鲁利马 TGW 的病毒抑制率。