Department of Environmental Health, Center for Public Health, Medical University of Vienna, Vienna, Austria.
Department of Epidemiology, Center for Public Health, Medical University of Vienna, Kinderspitalgasse 15, 1090, Vienna, Austria.
Wien Klin Wochenschr. 2019 May;131(9-10):200-204. doi: 10.1007/s00508-019-1476-7. Epub 2019 Mar 14.
After one of Austria's largest environmental scandals in 2014, which involved the release of hexachlorobenzene (HCB) in the Carinthian valley Görtschitztal, concerns about increased cancer rates have arísen in the affected local population. A descriptive study was conducted to examine the cancer incidence rates between 1983 and 2012. Data from the affected area (Görtschitztal, district St. Veit) were compared to data from the neighboring area within the same district and Carinthia excluding St. Veit, considering incidence rates of liver, lung, kidney, thyroid cancer and mesothelioma. Prostate cancer and carcinoma in situ were both included and excluded from overall cancer incidents in order to prevent potential bias due to screening programs. Considering the observed variability at an overall level, no conspicuous differences in cancer incidences could be found (Carinthia: 495, St. Veit West: 408, St. Veit East: 572 cases per 100,000 person-years in 2012). For some cancer types, e. g. liver, thyroid cancer and mesothelioma, the affected region showed a higher increase in rates than the neighboring area or Carinthia overall; however, these increased rates date back to a time prior to the HCB exposure, suggesting other carcinogenic influences, such as asbestos exposure from antecedent years.
在 2014 年奥地利最大的环境丑闻之一——加里西亚戈尔茨伊察塔尔（Görtschitztal）六氯苯（HCB）泄漏事件之后，受影响地区的当地居民开始担心癌症发病率上升。本研究旨在调查 1983 年至 2012 年期间的癌症发病率。将受影响地区（戈尔茨伊察塔尔，圣维特区）的数据与同一区的相邻地区以及不包括圣维特区的卡林西亚地区的数据进行了比较，比较的癌症类型包括肝癌、肺癌、肾癌、甲状腺癌和间皮瘤。前列腺癌和原位癌都包括在所有癌症病例中，以防止因筛查计划而导致的潜在偏倚。考虑到整体水平的观察到的变异性，未发现癌症发病率有明显差异（卡林西亚：2012 年每 100,000 人年 495 例；圣维特西部：408 例；圣维特东部：572 例）。对于某些癌症类型，如肝癌、甲状腺癌和间皮瘤，受影响地区的发病率增长高于相邻地区或整个卡林西亚地区；然而，这些增长的发病率可以追溯到 HCB 暴露之前的时期，表明存在其他致癌因素，如前几年的石棉暴露。
