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通过多学科心脏团队方法获得的冠状动脉疾病改善结果。

Enhanced outcomes for coronary artery disease obtained by a multidisciplinary heart team approach.

作者信息

Yamasaki Manabu, Abe Kohei, Horikoshi Rihito, Hoshino Eri, Yanagisawa Hiromi, Yoshino Kunihiko, Misumi Hiroyasu, Mizuno Atsushi, Komiyama Nobuyuki

机构信息

Department of Cardiovascular Surgery, St. Luke's International Hospital, 9-1 Akashicho, Chuoku, Tokyo, 104-8560, Japan.

Graduate School of Public Health, St. Luke's International University, Tokyo, Japan.

出版信息

Gen Thorac Cardiovasc Surg. 2019 Oct;67(10):841-848. doi: 10.1007/s11748-019-01108-4. Epub 2019 Mar 15.

Abstract

BACKGROUND

We implemented our multidisciplinary heart team (MHT) approach since 2012 for patients with coronary artery disease (CAD) and assessed the effectiveness of it by comparing outcomes in patients treated before and after the introduction of the MHT approach.

METHODS

Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for CAD were performed in 802 and 57 patients from 2009 to 2011 in Group NH, and were performed in 867 and 160 patients from 2012 to 2014 in Group H, respectively. The primary outcome was major adverse cardiovascular and cerebrovascular events (MACCE), defined as the composite of all-cause death, myocardial infarction, stroke, cardiac-related readmission and target vessel repeat revascularisation (TVR) for PCI or revascularisation on grafted vessels for CABG.

RESULTS

MACCE occurred significantly more often in Group NH than in Group H at 3 years postoperatively (28.1% vs 21.1%) (log rank P = 0.001). Cox regression analysis showed that the MHT approach [hazard ratio (HR), 0.737; 95% confidence interval (CI), 0.60-0.91; P = 0.004] and ejection fraction (HR 0.976; 95% CI, 0.97-0.98; P < 0.0001) were associated with significantly lower rates of MACCE events, while SYNTAX score (HR 1.023; 95% CI 1.00-1.03, P < 0.0001) and EuroSCORE II (HR 1.014, 95% CI 0.60-0.91, P = 0.004) were associated with a higher rate of MACCE events.

CONCLUSION

Our MHT approach was able to reduce the MACCE events of treatment for CAD. The dedicated MHT approach might be beneficial for patients with CAD.

摘要

背景

自2012年起,我们对冠心病(CAD)患者实施了多学科心脏团队(MHT)治疗方案,并通过比较引入MHT方案前后患者的治疗结果来评估其有效性。

方法

2009年至2011年,NH组802例和57例患者分别接受了经皮冠状动脉介入治疗(PCI)和冠状动脉旁路移植术(CABG)治疗CAD;2012年至2014年,H组867例和160例患者分别接受了上述治疗。主要结局是主要不良心血管和脑血管事件(MACCE),定义为全因死亡、心肌梗死、中风、心脏相关再入院以及PCI的靶血管再次血运重建(TVR)或CABG移植血管血运重建的综合结果。

结果

术后3年,NH组MACCE发生率显著高于H组(28.1%对21.1%)(对数秩检验P = 0.001)。Cox回归分析显示,MHT方案[风险比(HR),0.737;95%置信区间(CI),0.60 - 0.91;P = 0.004]和射血分数(HR 0.976;95% CI,0.97 - 0.98;P < 0.0001)与MACCE事件发生率显著降低相关,而SYNTAX评分(HR 1.023;95% CI 1.00 - 1.03,P < 0.0001)和欧洲心脏手术风险评估系统II(EuroSCORE II)(HR 1.014,95% CI 0.60 - 0.91,P = 0.004)与MACCE事件发生率较高相关。

结论

我们的MHT方案能够降低CAD治疗的MACCE事件。专门的MHT方案可能对CAD患者有益。

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