运动前皮质为步态修改规划期间信息的时间转换提供了基础。
Premotor Cortex Provides a Substrate for the Temporal Transformation of Information During the Planning of Gait Modifications.
机构信息
The Research Center for Brain Function and Medical Engineering, Asahikawa Medical University 2-1, 1-1, Midorigaoka-Higashi, Asahikawa, Japan.
Département de Neurosciences, Université de Montréal, Montréal, Québec, Canada.
出版信息
Cereb Cortex. 2019 Dec 17;29(12):4982-5008. doi: 10.1093/cercor/bhz039.
Abstract
We tested the hypothesis that the premotor cortex (PMC) in the cat contributes to the planning and execution of visually guided gait modifications. We analyzed single unit activity from 136 cells localized within layer V of cytoarchitectonic areas 6iffu and that part of 4δ within the ventral bank of the cruciate sulcus while cats walked on a treadmill and stepped over an obstacle that advanced toward them. We found a rich variety of discharge patterns, ranging from limb-independent cells that discharged several steps in front of the obstacle to step-related cells that discharged either during steps over the obstacle or in the steps leading up to that step. We propose that this population of task-related cells within this region of the PMC contributes to the temporal evolution of a planning process that transforms global information of the presence of an obstacle into the precise spatio-temporal limb adjustment required to negotiate that obstacle.
摘要
我们检验了这样一个假设，即猫的运动前皮层（PMC）有助于规划和执行视觉引导的步态修改。当猫在跑步机上行走并跨过向它们前进的障碍物时，我们分析了位于细胞构筑区域 6iffu 的 V 层内和十字形沟腹侧支的 4δ 部分内的 136 个细胞的单个单元活动。我们发现了丰富多样的放电模式，从与肢体无关的细胞到与步骤相关的细胞，范围从在障碍物前几步放电的细胞到在障碍物上的步骤中或在导致该步骤的步骤中放电的细胞。我们提出，PM 的这一区域内的这一群与任务相关的细胞有助于规划过程的时间演变，该过程将障碍物存在的全局信息转换为协商该障碍物所需的精确时空肢体调整。
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