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MxA is a clinically applicable biomarker for type I interferon activation in systemic lupus erythematosus and systemic sclerosis.

作者信息

Huijser Erika, van Helden-Meeuwsen Cornelia G, Groot Noortje, Bodewes Iris L A, Wahadat M Javad, Schreurs Marco W J, van Daele Paul L A, Dalm Virgil A S H, van Laar Jan A M, van Hagen P Martin, Waris Matti, Kamphuis Sylvia, Versnel Marjan A

机构信息

Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Department of Paediatric Rheumatology, Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands.

出版信息

Rheumatology (Oxford). 2019 Jul 1;58(7):1302-1303. doi: 10.1093/rheumatology/kez078.

DOI:10.1093/rheumatology/kez078
PMID:30879072
Abstract
摘要

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MxA is a clinically applicable biomarker for type I interferon activation in systemic lupus erythematosus and systemic sclerosis.MxA是系统性红斑狼疮和系统性硬化症中I型干扰素激活的一种临床适用生物标志物。
Rheumatology (Oxford). 2019 Jul 1;58(7):1302-1303. doi: 10.1093/rheumatology/kez078.
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Interferon score is increased in incomplete systemic lupus erythematosus and correlates with myxovirus-resistance protein A in blood and skin.干扰素评分在不完全性系统性红斑狼疮中增加,并与血液和皮肤中的抗粘液病毒蛋白 A 相关。
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