Núcleo de Pesquisa em Biodiversidade e Biotecnologia, Universidade Federal do Piauí, Parnaíba, PI, Brazil; Núcleo de Controle de Qualidade de Medicamentos e Correlatos, Departamento de Ciências Farmacêuticas, Universidade Federal de Pernambuco, Brazil.
Núcleo de Pesquisa em Biodiversidade e Biotecnologia, Universidade Federal do Piauí, Parnaíba, PI, Brazil.
Carbohydr Polym. 2019 Jun 1;213:176-183. doi: 10.1016/j.carbpol.2019.02.033. Epub 2019 Feb 14.
This work describes a solvent-free method for the chemical modification of cashew gum (Anacardium occidentale L.) using phthalic anhydride in different proportions with different reaction times. Four biopolymers were synthesized and characterized by FTIR, NMR, and elemental analysis. A computational chemistry study was conducted to understand better the reaction. Phthalated cashew gum was used in preparation of silver nanoparticles (AgNPs) by a conventional route, using sodium borohydride (NaBH) as reducing agent, and for green route. AgNPs were evaluated for antimicrobial activity and characterized by UV-Vis spectroscopy, FTIR, nanoparticle tracking analysis, Zeta Potential analysis, and atomic force microscopy. AgNPs produced by the green route had an average size of 51.9 nm and Zeta Potential of -55.8 mV, and AgNPs produced by the conventional method had an average size of 47.7 nm and Zeta Potential of -39.3 mV. AgNPs synthesized using phthalated cashew gum showed antimicrobial activity against Staphylococcus aureus and Escherichia coli.
本工作描述了一种在无溶剂条件下使用邻苯二甲酸酐对腰果胶（Anacardium occidentale L.）进行化学修饰的方法，邻苯二甲酸酐与腰果胶的比例和反应时间不同。合成了四种生物聚合物，并通过傅里叶变换红外光谱（FTIR）、核磁共振（NMR）和元素分析进行了表征。通过计算化学研究进一步了解了反应。使用邻苯二甲酸酐化的腰果胶通过常规途径（使用硼氢化钠（NaBH）作为还原剂）和绿色途径制备了银纳米粒子（AgNPs）。通过紫外-可见光谱、傅里叶变换红外光谱、纳米颗粒跟踪分析、Zeta 电位分析和原子力显微镜对 AgNPs 的抗菌活性进行了评估和表征。绿色途径制备的 AgNPs 的平均粒径为 51.9nm，Zeta 电位为-55.8mV，常规方法制备的 AgNPs 的平均粒径为 47.7nm，Zeta 电位为-39.3mV。使用邻苯二甲酸酐化的腰果胶合成的 AgNPs 对金黄色葡萄球菌和大肠杆菌表现出抗菌活性。
