[泪点和泪小管塞：适应证、疗效及安全性（文章的法语译文）]

[Punctal and canalicular plugs: Indications, efficacy and safety (French translation of the article)].

作者信息

Best A-L, Labetoulle M, Legrand M, M'garrech M, Barreau E, Rousseau A

机构信息

Service d'ophtalmologie, centre de référence maladies rares en ophtalmologie OPHTARA, hôpital Bicêtre, université Paris-Sud, DHU vision et handicap, Assistance publique-Hôpitaux de Paris, 78, rue du Général Leclerc, 94275 Le Kremlin-Bicêtre cedex, France; Immunologie des maladies virales et maladies auto-immunes (IMVA/Infrastructure IDMIT) UMR 1184, CEA, 92260 Fontenay-aux-Roses, France.

出版信息

J Fr Ophtalmol. 2019 Apr;42(4):404-414. doi: 10.1016/j.jfo.2018.10.003. Epub 2019 Mar 15.

DOI:10.1016/j.jfo.2018.10.003

PMID:30879835

Abstract

Lacrimal occlusion with punctal or canalicular plugs have been used to treat dry eye disease for more than 40 years. Indeed, punctal plugs constitute a safe and effective tool to retain the natural tear film and prolong the effect of tear substitutes. A wide variety of plugs is available, differing in their design, location (punctal versus canalicular) and their resorbability. There indications have increasingly broadened, and they are now one of the treatment options for numerous ocular surface diseases. Current research focuses on using punctal plugs for extended delivery of drugs to the ocular surface. This review addresses physiology of lacrimal drainage, available models of punctal plugs, their indications, practical details of prescribing and placing punctal and canalicular plugs, and possible complications.

摘要

使用泪点或泪小管塞进行泪道阻塞治疗干眼症已有40多年历史。事实上，泪点塞是保留天然泪膜和延长泪液替代物效果的一种安全有效的工具。有各种各样的塞子可供选择，它们在设计、位置（泪点与泪小管）和可吸收性方面有所不同。其适应证越来越广泛，现在已成为众多眼表疾病的治疗选择之一。目前的研究集中在使用泪点塞将药物延长递送至眼表。本综述阐述了泪液引流的生理学、现有的泪点塞模型、其适应证、开具和放置泪点及泪小管塞的实际细节以及可能的并发症。