Department of Epidemiology and Statistics, Hebei Key Laboratory of Environment and Human Health, School of Public Health, Hebei Medical University.
National Institutes for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention.
J Epidemiol. 2020 Mar 5;30(3):128-135. doi: 10.2188/jea.JE20180223. Epub 2019 Mar 16.
The prevalence of overweight is increasing dramatically worldwide. The aim of our study was to investigate the association of plain water intake (PWI) with the risk of new-onset overweight risk among Chinese adults.
A total of 3,200 adults aged 18-65 who were free of overweight at baseline were enrolled from China Health and Nutrition Survey (CHNS) cohort study in 2006-2011. The risk of new-onset overweight with different amounts of PWI per day was analyzed in this 5-year cohort. A multiple logistic regression model was used to assess the association of PWI and the risk of new-onset overweight and adjust for potential confounders. Moreover, dose-response models were developed to estimate the linear relationship.
During 5 years of follow-up, 1,018 incident cases were identified. Our analysis indicated an inverse association of more than 4 cups of PWI per day and the risk of new-onset overweight among normal weight individuals. Compared with participants who drank 2 to 3 cups PWI, the adjusted odds ratios (OR) of overweight were 0.741 (95% confidence interval [CI], 0.599-0.916) in participants who drank 4 to 5 cups PWI, and 0.547 (95% CI, 0.435-0.687) in participants who drank more than 6 cups PWI. The dose-response analysis showed that every cup of PWI was associated with a 6.5% and 8.4% decrease in the risk of new-onset overweight among men and women, respectively. The interactions of PWI and covariates on the risk of overweight were not found.
Drinking more than 4 cups (≈1 liter) per day of plain water is associated with decrease in the risk of new-onset overweight among normal-weight individuals.
超重的患病率在全球范围内急剧上升。我们的研究目的是调查中国成年人中白开水摄入量（PWI）与新发超重风险的关系。
共有 3200 名年龄在 18-65 岁之间、基线时无超重的成年人，来自中国健康与营养调查（CHNS）队列研究，该研究在 2006-2011 年进行。在这个 5 年的队列中，分析了每天不同 PWI 量与新发超重风险的关系。使用多因素 logistic 回归模型评估 PWI 与新发超重风险的关系，并调整潜在的混杂因素。此外，还建立了剂量反应模型来估计线性关系。
在 5 年的随访期间，共发现 1018 例新发病例。我们的分析表明，每天饮用超过 4 杯白开水与正常体重人群新发超重风险呈负相关。与饮用 2-3 杯水的参与者相比，饮用 4-5 杯水的参与者超重的调整比值比（OR）为 0.741（95%置信区间 [CI]，0.599-0.916），饮用超过 6 杯水的参与者的 OR 为 0.547（95% CI，0.435-0.687）。剂量反应分析表明，男性和女性每天每增加一杯 PWI，新发超重风险分别降低 6.5%和 8.4%。未发现 PWI 和协变量对超重风险的交互作用。
每天饮用超过 4 杯（约 1 升）白开水与正常体重人群新发超重风险降低有关。
