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治疗计划系统辅助的大孔径计算机断层扫描模拟器在经皮活检中的应用:放射治疗师的初步经验

Application of a treatment planning system-assisted large-aperture computed tomography simulator to percutaneous biopsy: initial experience of a radiation therapist.

作者信息

Lin Xiaoyi, Ma Liqin, Du Kaixin, Hong Junqiang, Luo Shuiying, Lai Youqun, Dai Yongliang, Kong Xiangquan

机构信息

Department of Radiation Oncology, Xiamen Humanity Hospital Fujian Medical University, Xiamen, Fujian Province, China.

Department of Radiation Oncology, Fujian Medical University Cancer Hospital, Fuzhou, Fujian Province, China.

出版信息

J Int Med Res. 2021 Jan;49(1):300060520983141. doi: 10.1177/0300060520983141.

Abstract

OBJECTIVE

To evaluate the application of treatment planning system (TPS)-assisted large-aperture computed tomography (CT) simulator to percutaneous biopsy.

METHODS

This retrospective study enrolled patients that underwent TPS-assisted large-aperture CT simulator-guided percutaneous biopsy from November 2018 to December 2019. Retrospective analyses of puncture accuracy were compared using paired -test and a Wilcoxon rank sum test. The risk factors for puncture accuracy and complications were identified.

RESULTS

A total of 38 patients were included in this study. There were no significant differences between the planned and actual puncture depth and angle. Pulmonary puncture was significantly associated with the accuracy of the puncture angle. The diagnostic rate of malignancy was 76% (29 of 38), of which 20 of 25 patients were in the group initially diagnosed with unconfirmed lesions and nine of 13 patients were in the group of treated patients that needed additional pathological analyses. For patients that underwent a pulmonary biopsy, 12 had minor pneumothorax and three suffered needle track bleeding. No other complications were observed. Regression analyses indicated a significant correlation between puncture angle and the incidence of pneumothorax.

CONCLUSION

TPS-assisted large-aperture CT simulator may improve the percutaneous biopsy procedure by combining the advantages of radiotherapy specialties with computer targeting.

摘要

目的

评估治疗计划系统(TPS)辅助大孔径计算机断层扫描(CT)模拟器在经皮活检中的应用。

方法

本回顾性研究纳入了2018年11月至2019年12月期间接受TPS辅助大孔径CT模拟器引导下经皮活检的患者。使用配对t检验和Wilcoxon秩和检验对穿刺准确性进行回顾性分析比较。确定穿刺准确性和并发症的危险因素。

结果

本研究共纳入38例患者。计划穿刺深度和角度与实际穿刺深度和角度之间无显著差异。肺穿刺与穿刺角度的准确性显著相关。恶性肿瘤的诊断率为76%(38例中的29例),其中25例最初诊断为未确诊病变的患者中有20例,13例需要额外病理分析的治疗患者中有9例。接受肺活检的患者中,12例有轻度气胸,3例有针道出血。未观察到其他并发症。回归分析表明穿刺角度与气胸发生率之间存在显著相关性。

结论

TPS辅助大孔径CT模拟器可通过将放射治疗专业优势与计算机靶向相结合来改善经皮活检程序。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d030/7829525/52ed7dd9c6e5/10.1177_0300060520983141-fig1.jpg

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