来自同一供体的2名肾移植受者可能感染供体来源的人34型腺病毒。
Probable Donor-Derived Human Adenovirus Type 34 Infection in 2 Kidney Transplant Recipients From the Same Donor.
作者信息
Pettengill Matthew A, Babu Tara M, Prasad Paritosh, Chuang Sally, Drage Michael G, Menegus Marilyn, Lamson Daryl M, Lu Xiaoyan, Erdman Dean, Pecora Nicole
机构信息
University of Rochester Medical Center, Rochester, New York.
Thomas Jefferson University, Philadelphia, Pennsylvania.
出版信息
Open Forum Infect Dis. 2018 Dec 26;6(3):ofy354. doi: 10.1093/ofid/ofy354. eCollection 2019 Mar.
Abstract
Human adenovirus type 34 (HAdV-34) infection is a recognized cause of transplant-associated hemorrhagic cystitis and, in rare cases, tubulointerstitial nephritis. The source of such infections is often difficult to assess, that is, whether acquired as a primary infection, exposure to a pathogen in the transplanted organ, or reactivation of an endogenous latent infection. We present here 2 cases of likely transplant-acquired HAdV-34 infection from the same organ donor, manifesting as tubulointerstitial nephritis in 1.
摘要
人腺病毒34型（HAdV-34）感染是移植相关出血性膀胱炎的已知病因，在罕见情况下也是肾小管间质性肾炎的病因。此类感染的来源通常难以评估，即难以确定是原发性感染、移植器官中接触病原体，还是内源性潜伏感染的激活。我们在此报告2例可能因同一器官供体而在移植后获得的HAdV-34感染病例，其中1例表现为肾小管间质性肾炎。
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