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输卵管肝样腺癌:一例报告并文献复习

Hepatoid adenocarcinoma of fallopian tube: A case report and review of the literature.

作者信息

Li Maomao, Yang Kaixuan, Wang Ping

机构信息

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University.

Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education.

出版信息

Medicine (Baltimore). 2019 Mar;98(11):e14534. doi: 10.1097/MD.0000000000014534.

Abstract

RATIONALE

Hepatoid adenocarcinoma (HAC) of the fallopian tubes is a rare malignant tumor in the female reproductive system.

PATIENT CONCERNS

An 81-year-old Chinese woman presented with an elevated serum alpha-fetoprotein (AFP) level.

DIAGNOSIS

Positron emission tomography-computed tomography (PET-CT) scan revealed a mass of approximately 47 × 27 mm located in the right adnexa. The tumor was diagnosed as a HAC arising from fallopian tube by immunohistochemical and histochemical technique.

INTERVENTIONS

This patient underwent surgical treatment including a bilateral adnexectomy and appendectomy. In addition, the patient underwent 5 cycles of postoperative chemotherapy.

OUTCOMES

The disease has recurred approximately six months after surgery and therefore, this patient will continue to be observed.

LESSONS

Up to this point, only 4 known cases of HAC originating in fallopian tube have been published in the English literature. Further studies are needed to better understand the clinical characteristics, the prognosis, and the pathological mechanism of HAC development in the fallopian tubes.

摘要

理论依据

输卵管肝样腺癌(HAC)是女性生殖系统中一种罕见的恶性肿瘤。

患者情况

一名81岁中国女性血清甲胎蛋白(AFP)水平升高。

诊断

正电子发射断层扫描-计算机断层扫描(PET-CT)显示右侧附件区有一约47×27mm的肿块。通过免疫组化和组织化学技术,该肿瘤被诊断为起源于输卵管的HAC。

干预措施

该患者接受了包括双侧附件切除术和阑尾切除术在内的手术治疗。此外,患者术后接受了5个周期的化疗。

结果

疾病在手术后约6个月复发,因此该患者将继续接受观察。

经验教训

截至目前,英文文献中仅发表了4例已知起源于输卵管的HAC病例。需要进一步研究以更好地了解输卵管HAC的临床特征、预后及病理发生机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b9c/6426549/eb500df4974e/medi-98-e14534-g001.jpg

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