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J Contemp Dent Pract. 2016 Jul 1;17(7):592-6.
3
Topical anesthesia.局部麻醉。
J Anaesthesiol Clin Pharmacol. 2015 Oct-Dec;31(4):450-6. doi: 10.4103/0970-9185.169049.
4
Efficacy of Benzocaine 20% Topical Anesthetic Compared to Placebo Prior to Administration of Local Anesthesia in the Oral Cavity: A Randomized Controlled Trial.20%苯佐卡因局部麻醉剂与安慰剂相比在口腔局部麻醉给药前的疗效:一项随机对照试验。
Anesth Prog. 2015 Summer;62(2):46-50. doi: 10.2344/0003-3006-62.2.46.
5
Effect of topical anesthesia on pain during infiltration injection and success of anesthesia for maxillary central incisors.表面麻醉对上颌中切牙浸润注射时疼痛及麻醉成功率的影响。
J Endod. 2012 Dec;38(12):1553-6. doi: 10.1016/j.joen.2012.08.011. Epub 2012 Sep 27.
6
Effect of time on clinical efficacy of topical anesthesia.时间对局部麻醉临床疗效的影响。
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Placebo theory and its implications for research and clinical practice: a review of the recent literature.安慰剂理论及其对研究和临床实践的启示:近期文献综述
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9
Evaluation of three topical anaesthetic agents against pain: a clinical study.三种局部麻醉剂抗疼痛效果的评估:一项临床研究。
Indian J Dent Res. 2006 Oct-Dec;17(4):155-60. doi: 10.4103/0970-9290.29871.
10
Sex differences in pain perception.疼痛感知中的性别差异。
Gend Med. 2005 Sep;2(3):137-45. doi: 10.1016/s1550-8579(05)80042-7.

上颌部外用苯佐卡因的疗效:一项随机对照试验。

Efficacy of Topical Benzocaine in Maxilla: A Randomized Controlled Trial.

作者信息

Rehman Nurain, Qazi Samir Riaz

机构信息

Institute of Dentistry, CMH Lahore Medical College.

Oral and Maxillofacial Surgeon, Lahore, Pakistan.

出版信息

Anesth Prog. 2019 Spring;66(1):24-29. doi: 10.2344/anpr-66-01-01.

DOI:10.2344/anpr-66-01-01
PMID:30883233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6424162/
Abstract

This study aims to compare the effect of topical anesthesia against the use of no topical agent on pain of needle penetration and local anesthesia deposition during buccal infiltration in anterior maxilla. In a randomized controlled trial, 100 adult participants were randomly allocated to the benzocaine group (received 20% benzocaine gel) and no benzocaine group (received no topical agent) prior to buccal infiltration in maxillary anterior teeth. A 27-gauge needle was used to deposit 2% lidocaine with 1:100,000 epinephrine. Pain of needle penetration and local anesthesia deposition was recorded separately using an 11-point Numeric Pain Rating Scale. Results showed that although 20% benzocaine significantly reduced pain on needle penetration during buccal infiltration in maxillary anterior teeth, the difference was small and the clinical significance is not clear. Topical anesthetic did not affect pain of local anesthetic deposition.

摘要

本研究旨在比较局部麻醉与不使用局部麻醉剂对上颌前部颊侧浸润麻醉时针刺疼痛及局部麻醉剂注射疼痛的影响。在一项随机对照试验中,100名成年参与者在上颌前牙颊侧浸润麻醉前被随机分配至苯佐卡因组(接受20%苯佐卡因凝胶)和无苯佐卡因组(不接受局部麻醉剂)。使用27号针头注射含1:100,000肾上腺素的2%利多卡因。使用11点数字疼痛评分量表分别记录针刺疼痛和局部麻醉剂注射疼痛。结果显示,虽然20%苯佐卡因显著减轻了上颌前牙颊侧浸润麻醉时的针刺疼痛,但差异较小,临床意义尚不清楚。局部麻醉剂对局部麻醉剂注射疼痛无影响。