Sara S J
Psychopharmacology (Berl). 1986;89(3):307-10. doi: 10.1007/BF00174365.
Rats were trained in a complex maze task for food reward. After a 25-day retention interval, they made more errors than at the last training trials. This forgetting was alleviated by pretest treatment with haloperidol. The same dose of haloperidol had no effect on acquisition or performance when injected during training. The results were replicated, but smaller doses were found to be inactive. The possibility that the effect might be mediated through the noradrenergic system is considered.
大鼠在一个复杂的迷宫任务中接受训练以获取食物奖励。在25天的保持间隔后，它们比上次训练试验时犯了更多错误。通过氟哌啶醇预测试处理可减轻这种遗忘。在训练期间注射相同剂量的氟哌啶醇对习得或表现没有影响。结果得到了重复，但发现较小剂量没有效果。研究考虑了这种效应可能通过去甲肾上腺素能系统介导的可能性。
