Am J Trop Med Hyg. 2019 May;100(5):1056-1057. doi: 10.4269/ajtmh.19-0084.
Brett-Major and others remind us that pathogen lists for emerging infectious diseases aid in the development of tools that target specific pathogens (e.g., vaccines) and help attract financial support. These lists tell us what we need to have, not what we need to do. The authors call for more research on ways to prevent these diseases (e.g., platform technologies for vaccines) and mitigate disease impact. Vaccines and new treatments that target individual pathogens have many limitations. However, we might save lives by treating patients with inexpensive generic drugs that target common features of the host response to infection. Undertaking research on this approach to treatment is what we need to do.
布雷特-马乔等人提醒我们，针对新发传染病的病原体清单有助于开发针对特定病原体的工具（例如疫苗），并有助于吸引财政支持。这些清单告诉我们需要什么，而不是需要做什么。作者呼吁开展更多研究，寻找预防这些疾病的方法（例如疫苗的平台技术）并减轻疾病的影响。针对个别病原体的疫苗和新疗法有许多局限性。然而，通过使用针对感染宿主反应的常见特征的廉价通用药物来治疗患者，我们可能会挽救生命。我们需要开展这项治疗方法的研究。
