哌嗪对青蛙中枢和外周胆碱能突触的作用。
Effect of piperazine on central and peripheral cholinergic synapses of the frog.
作者信息
Nistri A, Arenson M S
出版信息
Experientia. 1978 Aug 15;34(8):1046-7. doi: 10.1007/BF01915338.
PMID:308887
Abstract
The anthelmintic agent piperazine did not antagonize carbachol-induced depolarizations of the frog sartorius muscle but depressed root potentials and acetylcholine release from the frog spinal cord. We suggest that piperazine has a presynaptic site of action at central cholinergic nerve-terminals.
摘要
驱虫药哌嗪不会拮抗卡巴胆碱引起的青蛙缝匠肌去极化，但会抑制青蛙脊髓的根电位和乙酰胆碱释放。我们认为哌嗪在中枢胆碱能神经末梢有一个突触前作用位点。
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