Caimo A, Parodi C M, De Filippi S, Rabitti C, Cerri R, Risso M, Bacigalupo A, Castellaneta A, Marmont A
Acta Haematol. 1986;75(1):23-5. doi: 10.1159/000206074.
High-resolution chromosome banding studies were carried out on leukemic cells from a young patient with acute nonlymphocytic leukemia (ANLL), M2 of the FAB classification. A new chromosomal abnormality involving a translocation between chromosomes 3 and 21 was observed, i.e., t(3;21)(p14;q22). A complete remission was never obtained in spite of aggressive chemotherapy and the patient died 8 months after diagnosis.
对一名患有急性非淋巴细胞白血病(ANLL)(FAB分类为M2型)的年轻患者的白血病细胞进行了高分辨率染色体显带研究。观察到一种新的染色体异常,涉及3号和21号染色体之间的易位,即t(3;21)(p14;q22)。尽管进行了积极的化疗,但从未实现完全缓解,患者在诊断后8个月死亡。