Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China,
Liaoning Centre for Prenatal Diagnosis, Key Laboratory of Maternal-Fetal Medicine of Liaoning Province, Shenyang, China,
Ann Nutr Metab. 2019;74(3):215-223. doi: 10.1159/000499073. Epub 2019 Mar 19.
It is still controversial which anthropometric indicator could be the best predictor of the incident hypertension.
To examine the relative power of body mass index (BMI), waist circumference (WC), skinfold thickness, waist-to-hip ratio (WHR), and waist-to-height ratio (WHTR) in predicting the incidence of hypertension in Chinese adults.
Data were obtained from the China Health and Nutrition Survey. Overweight was defined as BMI ≥23 kg/m2 and general obesity as BMI ≥27.5 kg/m2. Abdominal obesity was defined by WC values ≥90 cm for males and ≥80 cm for females. Skinfold thickness, WHR, and WHTR were divided into low and high groups according to receiver operating characteristics. Cox regressions and nomograms were employed to compare the relative power of 5 indicators in predicting incident hypertension.
When all indicators were analyzed simultaneously, the best predictor of incident hypertension was general obesity (p < 0.001, adjusted hazard ratio [HR] 1.9, 95% CI 1.6-2.2). The results stratified by sex showed that BMI and WC were the more powerful predictors of hypertension in males (adjusted HR 1.8 and 1.3, 95% CI 1.4-2.3 and 1.1-1.5, respectively) as well as in females (adjusted HR 2.0 and 1.4, 95% CI 1.6-2.4 and 1.2-1.6, respectively).
BMI and WC may predict incident hypertension better than skinfold thickness, WHR, and WHTR in the Chinese population.
哪种人体测量指标最能预测高血压的发生仍存在争议。
检验体重指数(BMI)、腰围(WC)、体脂厚度、腰臀比(WHR)和腰高比(WHTR)在预测中国成年人高血压发生中的相对效力。
数据来自中国健康与营养调查。超重定义为 BMI≥23kg/m²,一般肥胖定义为 BMI≥27.5kg/m²。WC 值男性≥90cm、女性≥80cm 定义为腹型肥胖。根据受试者工作特征曲线将体脂厚度、WHR 和 WHTR 分为低分组和高分组。采用 Cox 回归和列线图比较 5 项指标预测新发高血压的相对效力。
当同时分析所有指标时,一般肥胖是新发高血压的最佳预测指标(p<0.001,调整后危险比 [HR]1.9,95%可信区间 1.6-2.2)。按性别分层的结果显示,BMI 和 WC 是男性(调整后 HR 1.8 和 1.3,95%可信区间 1.4-2.3 和 1.1-1.5)和女性(调整后 HR 2.0 和 1.4,95%可信区间 1.6-2.4 和 1.2-1.6)高血压更强的预测指标。
在中国人群中,BMI 和 WC 可能比体脂厚度、WHR 和 WHTR 更好地预测新发高血压。