School of Metallurgy and Materials, The University of Birmingham, Birmingham B15 2TT, UK; National Key Laboratory for Remanufacturing, AAAF, Beijing 100072, China.
School of Metallurgy and Materials, The University of Birmingham, Birmingham B15 2TT, UK.
Mater Sci Eng C Mater Biol Appl. 2019 Jun;99:150-158. doi: 10.1016/j.msec.2019.01.087. Epub 2019 Jan 22.
Silver is considered promising in medical devices to prevent infection due to its excellent properties of broad antibacterial spectrum and persistent antibacterial activity. Herein, silver impregnated functionally graded composite surfaces have been developed by a novel duplex plasma deposition technique, which combines the double glow sputtering process and active screen plasma nitriding process. The composite surfaces include a surface antibacterial layer and a bottom supporting layer, which are deposited simultaneously. The functionally graded structure endows the composite surfaces with antibacterial activity, combined with improved wear resistance. The multilayer structures were observed by scanning electron microscopy, and the graded distribution of silver and nitrogen was verified by glow discharge optical emission spectroscopy. X-ray diffraction and X-ray photoelectron spectroscopy were used to analyze the microstructures and chemical states of the components. Results from physical properties tests indicated that the composite surfaces have increased hardness, lower contact angles, excellent scratch resistance and wear resistance. The in-vitro antibacterial tests using the Gram-negative E. coli. NCTC 10418 also showed that over 99% of bacteria were killed after 5 h contacting with the composite surface.
银由于其广谱抗菌和持久抗菌活性的优异性能，被认为在医疗器械中具有很大的应用前景。本研究采用一种新颖的双辉等离子体沉积技术，将银浸渍功能梯度复合表面，该技术结合了双辉溅射工艺和活性屏等离子体渗氮工艺。复合表面包括一个表面抗菌层和一个底部支撑层，它们是同时沉积的。功能梯度结构赋予复合表面抗菌活性，同时结合了耐磨性的提高。通过扫描电子显微镜观察了多层结构，并通过辉光放电发射光谱验证了银和氮的梯度分布。X 射线衍射和 X 射线光电子能谱用于分析成分的微观结构和化学状态。物理性能测试结果表明，复合表面具有较高的硬度、较低的接触角、优异的耐刮擦性和耐磨性。使用革兰氏阴性大肠杆菌 NCTC 10418 的体外抗菌试验也表明，与复合表面接触 5 小时后，超过 99%的细菌被杀死。
