Klein Jan Philipp, Berger Thomas, Hautzinger Martin, Lutz Wolfgang, Rose Matthias, Späth Christina, Schröder Johanna, Hohagen Fritz, Moritz Steffen
Fortschr Neurol Psychiatr. 2019 Mar;87(3):172-180. doi: 10.1055/a-0849-9838. Epub 2019 Mar 19.
Only about half of those suffering from a depressive disorder seek treatment. Self-management interventions are one way to reduce this treatment gap. These interventions are mostly based on evidence-based techniques of cognitive behavioural therapy, which are taught by a computer program instead of a therapist. Numerous studies have shown the effectiveness of these interventions. However, these studies also raise a number of questions. These concern the efficacy both in the external rating and in the long-term course and the efficacy in severe depressive symptoms or in combination with antidepressant medication. Finally, the question arises as to the use of these interventions in patients in clinical practice and in people who are not particularly Internet-savvy. We addressed these questions in a large randomized study (EVIDENT study). This study investigated the efficacy of Intervention deprexis®. The results of this study are summarised in this overview and placed in the context of other interventions available in Germany.
患有抑郁症的人中只有约一半会寻求治疗。自我管理干预措施是缩小这一治疗差距的一种方法。这些干预措施大多基于认知行为疗法的循证技术,由计算机程序而非治疗师进行传授。大量研究已表明这些干预措施的有效性。然而,这些研究也提出了一些问题。这些问题涉及外部评定和长期病程中的疗效,以及重度抑郁症状或与抗抑郁药物联合使用时的疗效。最后,出现了这些干预措施在临床实践中的患者以及不太精通互联网的人群中的使用问题。我们在一项大型随机研究(EVIDENT研究)中解决了这些问题。这项研究调查了deprexis®干预措施的疗效。本综述总结了这项研究的结果,并将其置于德国现有的其他干预措施的背景下。