Fletcher J P, Little J M, Walker P J
Aust N Z J Surg. 1986 Feb;56(2):117-20. doi: 10.1111/j.1445-2197.1986.tb01866.x.
Delayed hypersensitivity skin test reaction was evaluated using Multitest CMI, an implement which provides seven standardized antigens in a single application. Eighty-two patients requiring Total Parenteral Nutrition for a variety of conditions were studied. The incidence of anergy was 65%. Seven anergic patients died, but there were no deaths in the reactive group, this difference being significant (P = 0.04). There was a significant association of anergy with carcinoma (P = 0.007) and anergic patients with carcinoma had a significantly greater risk of dying than reactive patients without carcinoma (P = 0.038). Anergic patients also had significantly lower nutritional parameters of serum albumin (P = 0.04), transferrin (P less than 0.001), absolute lymphocyte count (P = 0.009) and mid-arm muscle circumference (P = 0.02) compared to the reactive group.
使用多测试CMI评估迟发型超敏皮肤试验反应，该仪器可在一次应用中提供七种标准化抗原。研究了82名因各种病症需要全胃肠外营养的患者。无反应性的发生率为65%。7名无反应性患者死亡，但反应性组无死亡病例，这一差异具有显著性（P = 0.04）。无反应性与癌症之间存在显著关联（P = 0.007），患有癌症的无反应性患者比无癌症的反应性患者死亡风险显著更高（P = 0.038）。与反应性组相比，无反应性患者的血清白蛋白（P = 0.04）、转铁蛋白（P < 0.001）、绝对淋巴细胞计数（P = 0.009）和上臂中部肌肉周长（P = 0.02）等营养参数也显著更低。
