Aktoz Fatih, Ozyuncu Ozgur, Tanacan Atakan, Fadiloglu Erdem, Unal Canan, Soyer Tutku, Celik Tolga, Beksac Mehmet Sinan
a Division of Perinatology, Department of Obstetrics and Gynecology, Hacettepe University Hospital , Ankara , Turkey.
b Department of Pediatric Surgery, Hacettepe University Hospital , Ankara , Turkey.
Fetal Pediatr Pathol. 2019 Aug;38(4):282-289. doi: 10.1080/15513815.2019.1585501. Epub 2019 Mar 20.
To evaluate and compare the outcomes of pregnancies with prenatally detected gastroschisis and omphalocele. We retrospectively evaluated prenatally detected gastroschisis and omphalocele cases. Cases were compared in terms of maternal demographic and clinical characteristics as well as pregnancy and neonatal outcomes. This study consisted of 17 gastroschisis and 30 omphalocele cases. Only one case with gastroschisis was terminated due to additional severe limb deformities. Seventeen out of 30 cases of omphalocele were terminated for various reasons (56.7%). All patients with gastroschisis had surgical repair, while 8 out of 13 omphalocele cases had surgery. One patient with an omphalocele died after surgery due to sepsis. Six cases of gastroschisis also died in the neonatal period due to various reasons (6/16, 37.5%). Additional genetic disorders are more frequent in those with omphalocele cases, and they are more frequently terminated during gestation that the gastroschisis fetuses.
评估并比较产前诊断为腹裂和脐膨出的妊娠结局。我们回顾性评估了产前诊断为腹裂和脐膨出的病例。对病例在孕产妇人口统计学和临床特征以及妊娠和新生儿结局方面进行了比较。本研究包括17例腹裂病例和30例脐膨出病例。仅1例腹裂病例因合并严重肢体畸形而终止妊娠。30例脐膨出病例中有17例因各种原因终止妊娠（56.7%）。所有腹裂患者均接受了手术修复，而13例脐膨出病例中有8例接受了手术。1例脐膨出患者术后因败血症死亡。6例腹裂病例也因各种原因在新生儿期死亡（6/16，37.5%）。脐膨出病例中额外的遗传疾病更为常见，并且与腹裂胎儿相比，它们在妊娠期更常被终止妊娠。
