a Department of Ophthalmology, Faculty of Medicine, Juntendo University , Tokyo , Japan.
Curr Eye Res. 2019 Aug;44(8):921-924. doi: 10.1080/02713683.2019.1597892. Epub 2019 Mar 28.
: Venting slits are widely used as an effective method to avoid the high intraocular pressure (IOP) phase immediately after the implantation of non-valved glaucoma drainage devices. However, there have been no detailed reports comparing the types of needles used and the numbers of slits made. In this study we investigated the effects of different needle types and the number of venting slits. : IOP was measured using a Keyence NR-600 transducer connected to the limbus of a pig eye with a 27G needle. A microsyringe pump was also connected to the corneal limbus using a 27 G needle to make a continuous perfusion system at the rate of 200 μl/hr. The silicone tube of a Baerveldt glaucoma drainage implant (BG101-350) was ligated near the plate and then implanted in the anterior chamber of the pig eye. The tube was covered with scleral tissue of another pig eye after 1 or 3 venting slits were created in the middle of the outer diameter using different types of needles (7-0 Vicryl®, 7-0 PDSⅡ®, 5-0 PDSⅡ®, 3-0 PDS Plus®). IOP measurement was started from 50 mmHg and then we monitored the chronological changes of IOP for 15 minutes. : The IOPs at 15 minutes after continuous perfusion with the venting slits made using 7-0 Vicryl needles were 29.0 ± 2.5 mmHg (1 slit) and 23.1 ± 8.3 mmHg (3 slits). The IOPs were 23.1 ± 3.1 mmHg and 23.5 ± 4.7 mmHg with 7-0 PDS needles (1 slit and 3 slits, respectively), 21.8 ± 2.2 mmHg and 20.8 ± 4.3 mmHg with 5-0 PDS needles (1 slit and 3 slits, respectively), and with 3-0 PDS needles they were 12.2 ± 3.0 mmHg for one slit and 13.2 ± 3.5 mmHg for 3 slits. : Usage of a round (PDS) needles produces more predictable IOP than a spatulated (Vicryl) needle.
排气槽被广泛用作一种有效的方法，以避免在非瓣膜性青光眼引流装置植入后立即出现高眼内压（IOP）期。然而，目前还没有详细的报告比较使用的针类型和制造的排气槽数量。在这项研究中，我们研究了不同针类型和排气槽数量的影响。
使用连接到猪眼角膜缘的 Keyence NR-600 换能器测量 IOP，使用 27G 针。还使用 microsyringe 泵通过 27G 针连接到角膜缘，以 200μl/hr 的速度建立连续灌注系统。将 Baerveldt 青光眼引流植入物（BG101-350）的硅胶管结扎在靠近板的位置，然后将其植入猪眼的前房。在管的外径中间用不同类型的针（7-0 Vicryl®、7-0 PDSⅡ®、5-0 PDSⅡ®、3-0 PDS Plus®）制造 1 或 3 个排气槽后，将另一只猪眼的巩膜组织覆盖在管上。从 50mmHg 开始测量 IOP，然后监测 15 分钟内 IOP 的时间变化。
使用 7-0 Vicryl 针制造排气槽后，连续灌注 15 分钟后的 IOP 分别为 29.0±2.5mmHg（1 个槽）和 23.1±8.3mmHg（3 个槽）。使用 7-0 PDS 针分别为 23.1±3.1mmHg 和 23.5±4.7mmHg（1 个槽和 3 个槽），使用 5-0 PDS 针分别为 21.8±2.2mmHg 和 20.8±4.3mmHg（1 个槽和 3 个槽），使用 3-0 PDS 针分别为 12.2±3.0mmHg 用于 1 个槽和 13.2±3.5mmHg 用于 3 个槽。
使用圆形（PDS）针产生的 IOP 比尖形（Vicryl）针更可预测。
