Children's Allergy Service, Evelina London Children's Hospital, Guy's and St. Thomas' NHS Foundation Trust.
Pediatric Allergy Group, Department of Women and Children's Health, School of Life Course Sciences.
Curr Opin Allergy Clin Immunol. 2019 Jun;19(3):224-228. doi: 10.1097/ACI.0000000000000531.
The following article provides an overview of food-dependent exercise-induced anaphylaxis (FD-EIAn). The review focuses on the epidemiology, pathophysiology, and clinical findings of FD-EIAn and details current practice in terms of the investigation, management, and treatment options available.
The management of FD-EIAn has not changed significantly over the last few years and still requires careful investigation by an experienced clinician to ensure that the correct diagnosis is made and appropriate treatment is given. Although new therapies such as synthetic prostaglandin E1 analogs and IgE monoclonal antibodies have been trialed as treatment options for FD-EIAn, the mainstay of treatment remains the graded reintroduction to exercise in a supervised setting.
FD-EIAn is a rare but serious condition that can have a significant impact on patients' lives. This review aims to discuss new relevant research into this field to help guide clinicians in managing this condition.
本文概述了食物依赖运动诱发的过敏反应(FD-EIAn)。综述重点介绍了 FD-EIAn 的流行病学、病理生理学和临床发现,并详细介绍了目前在调查、管理和治疗选择方面的实践情况。
过去几年中,FD-EIAn 的管理并没有发生重大变化,仍需要有经验的临床医生进行仔细调查,以确保做出正确的诊断并给予适当的治疗。尽管已经尝试了新的疗法,如合成前列腺素 E1 类似物和 IgE 单克隆抗体作为 FD-EIAn 的治疗选择,但治疗的主要方法仍然是在监督环境下逐渐重新进行运动。
FD-EIAn 是一种罕见但严重的疾病,会对患者的生活产生重大影响。本综述旨在讨论该领域的新相关研究,以帮助指导临床医生管理该疾病。