Nocerino Rita, Carucci Laura, Coppola Serena, Cecere Gaetano, Micillo Maria, Castaldo Tina, Russo Stefania, Sandomenico Marialuisa, Marino Antonio, Gualano Renato, Ercolini Paola, Capasso Antonella, Bedogni Giorgio, Berni Canani Roberto
Department of Translational Medical Science, University of Naples Federico II, Naples, Italy.
ImmunoNutritionLab at CEINGE Advanced Biotechnologies, University of Naples Federico II, Naples, Italy.
J Allergy Clin Immunol Glob. 2024 Mar 26;3(3):100246. doi: 10.1016/j.jacig.2024.100246. eCollection 2024 Aug.
Updated epidemiologic data are important for defining effective public health strategies for pediatric food allergy (FA).
The Epidemiology of Paediatric Italian Food Allergy (EPIFA) study was designed to investigate the epidemiology of pediatric FA in one of the most heavily populated Italian regions.
A retrospective cohort study was performed in collaboration with family pediatricians aimed at investigating the epidemiology of Italian pediatric FA during 2009 to 2021. Family pediatricians in the Campania region were invited to use the Google Forms platform for online compilation of data forms. Data forms were reviewed by experienced pediatric allergists at the coordinating center.
A total population of 105,151 subjects (aged 0-14 years) was screened during the study period. Data from 752 FA patients were evaluated. A progressive increase in FA incidence and prevalence was observed from 2009 to 2021, with a relative increase up to 34% and 113.6%, respectively, at the end of study period. The relative increase in FA prevalence was higher in the 0-3-year-old age group in the same study period (+120.8%). The most frequent allergens were cow's milk, hen's egg, and nuts.
The results of the EPIFA study showed an increase in pediatric FA incidence and prevalence from 2009 to 2021 in Italy. These results underline the necessity of new effective strategies for preventing and managing these conditions.
更新后的流行病学数据对于确定有效的儿童食物过敏（FA）公共卫生策略至关重要。
意大利儿童食物过敏流行病学（EPIFA）研究旨在调查意大利人口最密集地区之一的儿童食物过敏流行病学情况。
与家庭儿科医生合作开展了一项回顾性队列研究，旨在调查2009年至2021年期间意大利儿童食物过敏的流行病学情况。邀请坎帕尼亚地区的家庭儿科医生使用谷歌表单平台在线填写数据表单。数据表单由协调中心经验丰富的儿科过敏症专科医生进行审核。
在研究期间共筛查了105,151名受试者（年龄0至14岁）。对752名食物过敏患者的数据进行了评估。从2009年到2021年观察到食物过敏发病率和患病率呈逐步上升趋势，在研究期末相对增幅分别高达34%和113.6%。在同一研究期间，0至3岁年龄组食物过敏患病率的相对增幅更高（+120.8%）。最常见的过敏原是牛奶、鸡蛋和坚果。
EPIFA研究结果显示，2009年至2021年期间意大利儿童食物过敏的发病率和患病率有所上升。这些结果强调了制定新的有效策略来预防和管理这些疾病的必要性。
