破伤风类毒素被动免疫对人体的作用。
The effect of passive immunization against tetanus toxoid in man.
作者信息
Plassara M, Mandalenaki C, Papathanassiou E, Vrachnou E, Athanassiades P
出版信息
Immunology. 1978 Sep;35(3):567-70.
Abstract
The present study deals with the immunological response in man after passive immunization against tetanus toxoid. Treatment of man with equine antitetanus serum stimulates a rise of E rosette-forming T lymphocytes. The level of IgG also rises while the level of IgM falls. It is assumed that the foreign globulin acts as an antigen that evokes the T lymphocytes' co-operation for the humoral immune response with a switch from IgM to IgG synthesis.
摘要
本研究探讨了人体被动免疫破伤风类毒素后的免疫反应。用人抗破伤风血清治疗人体会刺激形成E玫瑰花结的T淋巴细胞数量增加。IgG水平升高，而IgM水平下降。据推测，外源球蛋白作为一种抗原，可引发T淋巴细胞的协同作用，以促进体液免疫反应，使免疫球蛋白的合成从IgM转换为IgG。
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本文引用的文献
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Specificity of enhanced immunological sensitization of mice following injections of antigens and specific antisera.注射抗原和特异性抗血清后小鼠增强免疫致敏的特异性。
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