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[破伤风类毒素液体疫苗皮下免疫后的T细胞动力学及体液免疫反应进程]

[T-cell kinetics and course of humoral immune response following subcutaneous immunization with tetanus toxoid fluid vaccine].

作者信息

Thilo W, Seeger E, Kraskina N A, Jentsch P, Fritze S, Beinlich R, Fischer R, Sowa W

出版信息

Zentralbl Chir. 1983;108(14):865-74.

PMID:6605009
Abstract

Revaccinations with tetanus toxoid fluid vaccine were performed including different groups of volunteers (aged, diabetics, rheumatics). The kinetics of T-cells were demonstrated by rosette technique in a period of 63 days after revaccination. The content of tetanus antitoxin was estimated by the mouse standard neutralization test. T-cell kinetics were different in the investigated groups, probably influenced by age, illness, therapy etc. Only those patients among the aged who were in bad health showed a relatively low humoral booster reaction.

摘要

对包括不同志愿者群体(老年人、糖尿病患者、风湿病患者)进行破伤风类毒素液体疫苗再接种。再接种后63天内,通过玫瑰花结技术展示T细胞动力学。通过小鼠标准中和试验评估破伤风抗毒素的含量。在受调查的群体中,T细胞动力学有所不同,可能受到年龄、疾病、治疗等因素的影响。只有健康状况不佳的老年患者表现出相对较低的体液增强反应。

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1
[T-cell kinetics and course of humoral immune response following subcutaneous immunization with tetanus toxoid fluid vaccine].[破伤风类毒素液体疫苗皮下免疫后的T细胞动力学及体液免疫反应进程]
Zentralbl Chir. 1983;108(14):865-74.
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