Fertility Clinic, CUB-Hôpital Erasme and Research Laboratory on Human Reproduction, Université Libre de Bruxelles (U.L.B.), Brussels, Belgium.
Department of Medical Oncology, U.O.C. Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino.
Curr Opin Oncol. 2019 Jul;31(4):259-267. doi: 10.1097/CCO.0000000000000540.
To provide an up-to-date overview on indications, efficacy and safety of the existing fertility preservation strategies as well as on the features and management of sexual dysfunction in young adult women with newly diagnosed cancer.
Because of the improved life expectancy of cancer survivors, a growing attention should be given to the side effects of anticancer treatments. Among young cancer patients, risk of infertility and sexual dysfunction are of great concern.
As advocated by guidelines, patients need to be thoroughly informed of potential side effects of treatment before starting them. On this regard, efforts should be made to improve the counseling of young adult patients around fertility and sexuality. Fertility preservation strategies should be properly and extensively explained to all young patients, weighting the pros and cons to choose the more appropriate options for each situation. In addition, discussing sexual dysfunction and delivering sexual rehabilitation for cancer survivors not only allows for renewal of sexual function but can also promote increased quality of life and help women create a new and satisfying chapter in their life for many years after cancer.
提供最新的关于现有生育力保存策略的适应证、疗效和安全性的概述，以及年轻成年女性新发癌症患者的性功能障碍的特征和管理。
由于癌症幸存者的预期寿命延长，应该更加关注抗癌治疗的副作用。在年轻的癌症患者中，不孕和性功能障碍的风险备受关注。
正如指南所倡导的，在开始治疗前，患者需要充分了解治疗的潜在副作用。在这方面，应该努力改善对年轻成年患者的生育和性方面的咨询。应该向所有年轻患者充分解释生育力保存策略，权衡利弊，为每种情况选择更合适的方案。此外，讨论性功能障碍并为癌症幸存者提供性康复治疗不仅可以恢复性功能，还可以提高生活质量，帮助女性在癌症后多年创造新的、满意的生活篇章。
