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金属块增强术在翻修全膝关节置换术(TKA)中治疗大型非包容性骨缺损的适用性

Suitability of Metal Block Augmentation for Large Uncontained Bone Defect in Revision Total Knee Arthroplasty (TKA).

作者信息

Kang Kwan Su, Tien Trinh Ngoc, Lee Myung Chul, Lee Kwon-Yong, Kim Bongju, Lim Dohyung

机构信息

Department of Research & Development, Medical Device Development Center, OSONG Medical Innovation Foundation, Cheongju 28160, Korea.

Department of Mechanical Engineering, Sejong University, Seoul 05006, Korea.

出版信息

J Clin Med. 2019 Mar 19;8(3):384. doi: 10.3390/jcm8030384.

Abstract

This study was performed to determine whether metal block augmentation is suitable for large uncontained bone defect via evaluations of differences in biomechanical characteristics among the configurations of metal block augmentations for medium or large uncontained bone defects in revision total knee arthroplasty (TKA). Three-dimensional finite element (FE) models of the proximal tibia with revision TKA were developed and analyzed considering the configurations of the metal block augmentations for medium and large uncontained bone defects. To identify differences in biomechanical characteristics according to the configurations of metal block augmentations, the stress transfer, strain distribution, and peak von Mises stresses (PVMSs) were assessed. Large and medium uncontained bone defects had similar ranges of strain below the critical bone-damage strain for the metal block augmentations, but the strain distribution characteristics differed in response to the metal block-augmentation configurations. PVMSs exceeding the yield strength of the bone cement for the single metal block-augmentation configurations were, on average, 1.4 times higher than those for double metal block-augmentation configurations for both medium and large uncontained bone defects. These findings suggest that metal block augmentation may be suitable for large uncontained bone defects (≤20 mm), compared with the results obtained for metal block augmentation used in medium uncontained bone defects (≤10 mm). If possible, double metal block augmentation is recommended for both medium and large uncontained bone defects rather than single metal block augmentation. It is also recommended that the metal block augmentation should be customized to meet the contact characteristics with the cortical bone, thereby ensuring better stress transfer and reducing the risk of the bone resorption due to stress shielding and bone-cement failure.

摘要

本研究旨在通过评估翻修全膝关节置换术(TKA)中用于中大型非包容性骨缺损的金属块增强结构之间的生物力学特性差异,来确定金属块增强是否适用于大型非包容性骨缺损。建立并分析了带有翻修TKA的胫骨近端三维有限元(FE)模型,同时考虑了用于中大型非包容性骨缺损的金属块增强结构。为了识别根据金属块增强结构的生物力学特性差异,评估了应力传递、应变分布和峰值冯·米塞斯应力(PVMSs)。对于金属块增强,中大型非包容性骨缺损在临界骨损伤应变以下具有相似的应变范围,但应变分布特征因金属块增强结构而异。对于中大型非包容性骨缺损,单金属块增强结构的PVMSs超过骨水泥屈服强度的平均值,比双金属块增强结构高1.4倍。这些发现表明,与用于中大型非包容性骨缺损(≤10 mm)的金属块增强结果相比,金属块增强可能适用于大型非包容性骨缺损(≤20 mm)。如果可能,对于中大型非包容性骨缺损,建议采用双金属块增强而非单金属块增强。还建议对金属块增强进行定制,以满足与皮质骨的接触特性,从而确保更好的应力传递,并降低因应力屏蔽和骨水泥失效导致骨吸收的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/067a/6462980/d0601d0ddd2b/jcm-08-00384-g001.jpg

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