a Cognitive Neuroscience and Neuropsychiatry Section, University College London Great Ormond Street Institute of Child Health , London , UK.
Cogn Neurosci. 2019 Jul-Oct;10(4):215-217. doi: 10.1080/17588928.2019.1593123. Epub 2019 Mar 21.
Cooper, Greve, and Henson (this issue) conclude that hippocampal-independent learning, as operationalised by 'fast mapping' (FM), is unlikely to facilitate learning in adults. We provide evidence from patients with Developmental Amnesia (DA), who acquire language and semantic knowledge despite early hippocampal pathology. We administered an FM paradigm to three patients with DA and controls. Patients showed no benefit of FM compared to explicit encoding. These data support the conclusion that FM is unlikely to facilitate learning in amnesia, regardless of age at onset. Hippocampal-independent learning may be possible in adults with DA, but such learning requires a prolonged consolidation period.
库珀、格雷夫和亨森（本期）得出结论，海马体独立性学习（通过快速映射实现）不太可能促进成年人的学习。我们提供了来自发展性遗忘症（DA）患者的证据，这些患者尽管存在早期海马体病变，但仍能获得语言和语义知识。我们对三名 DA 患者和对照组进行了快速映射范式测试。与显性编码相比，患者并未从快速映射中受益。这些数据支持了这样的结论，即快速映射不太可能促进遗忘症患者的学习，无论发病年龄如何。患有 DA 的成年人可能具有海马体独立性学习能力，但这种学习需要延长巩固期。
